Sugi Predict

Sugi Predict / Compounds / SCHEMBL635541

SCHEMBL635541

SCHEMBL635541

NCc1ncc(C(F)(F)F)cc1Cl

nearest known ligand 0.58

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 1/20 0.58
▸ L3MBTL1 Q9Y468 1/20 0.58
▸ ALDH1A1 P00352 6/20 0.53
▸ KMT2A Q03164 2/20 0.52
▸ HTT P42858 2/20 0.50
▸ PLAU P00749 1/20 0.50
▸ KDM4E B2RXH2 1/20 0.50
▸ POLB P06746 1/20 0.50
▸ SMN1; SMN2 Q16637 1/20 0.50
▸ RAB9A P51151 1/20 0.50
▸ GAA P10253 2/20 0.47
▸ MEN1 O00255 1/20 0.47
▸ NPSR1 Q6W5P4 1/20 0.47
▸ GLA P06280 1/20 0.45
▸ CYP1A2 P05177 1/20 0.45
▸ CYP3A4 P08684 1/20 0.45
▸ CYP2D6 P10635 1/20 0.45
▸ CYP2C19 P33261 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31255260 1.00 TDP1 (0.58) TDP1L3MBTL1ALDH1A1KMT2AHTT
Hydrochloric Acid SCHEMBL637924 0.98 TDP1 (0.56) TDP1L3MBTL1ALDH1A1KMT2AHTT
Hydrochloric Acid SCHEMBL6157878 0.98 TDP1 (0.56) TDP1L3MBTL1ALDH1A1KMT2AHTT
Hydrochloric Acid SCHEMBL16165936 0.98 TDP1 (0.56) TDP1L3MBTL1ALDH1A1KMT2AHTT
Water SCHEMBL28174658 0.96 TDP1 (0.55) TDP1L3MBTL1ALDH1A1KMT2AHTT
Sulfuric Acid SCHEMBL18191278 0.91 KMT2A (0.56) TDP1L3MBTL1ALDH1A1KMT2AHTT
Acetic Acid SCHEMBL5046683 0.89 KMT2A (0.55) TDP1L3MBTL1ALDH1A1KMT2AHTT
Acetic Acid SCHEMBL28417972 0.88 KMT2A (0.54) TDP1L3MBTL1ALDH1A1KMT2AHTT
Acetic Acid SCHEMBL28393632 0.87 KMT2A (0.53) TDP1L3MBTL1ALDH1A1KMT2AHTT
SCHEMBL1122017 0.86 TDP1 (0.55) TDP1L3MBTL1ALDH1A1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 226 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3713917-B1 PROCESS FOR THE PREPARATION OF FLUOPICOLIDE BAYER AG (DE) 2025-07-02 — — EP claimed
CN-118772049-B Preparation process of 3-chloro-2-aminoethyl-5-trifluoromethyl pyridine 山东滨农科技有限公司 2025-04-11 — — CN claimed
CN-118772049-A Preparation process of 3-chloro-2-aminoethyl-5-trifluoromethyl pyridine 山东滨农科技有限公司 2024-10-15 — — CN claimed
CN-116854628-B Fluopicolide hapten, artificial antigen and antibody as well as preparation methods and application thereof 深圳凯吉星农产品检测认证有限公司 2024-04-12 — — CN claimed
CN-116924974-A Preparation method of fluopicolide 天津均凯农业科技有限公司 2023-10-24 — — CN claimed
CN-116854628-A Fluopicolide hapten, artificial antigen and antibody as well as preparation methods and application thereof 深圳凯吉星农产品检测认证有限公司 2023-10-10 — — CN claimed
CN-115819330-A Method for continuously preparing 2-aminomethyl-3-chloro-5-trifluoromethylpyridine 天津均凯农业科技有限公司 2023-03-21 — — CN claimed
CN-115784976-A Improved preparation method of fluopicolide 武威广达科技有限公司 2023-03-14 — — CN claimed
EP-3288922-B1 CATALYTIC HYDROGENATION OF SUBSTITUTED CYANOPYRIDINES AND PROCESS FOR PREPARING SUBSTITUTED PYRIDYLMETHYLBENZAMIDES BAYER CROPSCIENCE AG (DE) 2021-12-22 — — EP claimed
US-10781176-B2 Catalytic hydrogenation of substituted cyanopyridines and process for preparing substituted pyridylmethylbenzamides BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) 2020-09-22 — — US claimed
US-7232911-B2 Process for the preparation of 2-aminomethylpyridine derivative BAYER CROPSCIENCE S.A. (FR) 2007-06-19 — — US claimed
EP-1565440-B1 NOVEL PROCESS FOR THE PREPARATION OF 2-AMINOMETHYLPYRIDINE DERIVATIVE BAYER CROPSCIENCE SA (FR) 2006-12-20 — — EP claimed
US-20060100441-A1 Process for the preparation of 2-aminomethylpyridine derivative BAYER CROPSCIENCE LIMITED (GB) 2006-05-11 — — US claimed
US-20060004206-A1 Novel process for the preparation of 2-aminomethylpyridine derivative BAYER CROPSCIENCE S.A. (FR) 2006-01-05 — — US claimed
EP-1565440-A1 NOVEL PROCESS FOR THE PREPARATION OF 2-AMINOMETHYLPYRIDINE DERIVATIVE Bayer CropScience S.A. (FR) 2005-08-24 — — EP claimed
EP-1565441-A2 PROCESS FOR THE PREPARATION OF 2-AMINOMETHYLPYRIDINE DERIVATIVE Bayer CropScience S.A. (FR) 2005-08-24 — — EP claimed
WO-2004065359-A2 PROCESS FOR THE PREPARATION OF 2-AMINOMETHYLPYRIDINE DERIVATIVE BAYER CROPSCIENCE S.A. (FR) 2004-08-05 — — WO claimed
WO-2004046114-A1 NOVEL PROCESS FOR THE PREPARATION OF 2-AMINOMETHYLPYRIDINE DERIVATIVE BAYER CROPSCIENCE S.A. (FR) 2004-06-03 — — WO claimed
EP-1422220-A1 Process for the preparation of 2-aminomethylpyridine derivative Bayer CropScience SA (FR) 2004-05-26 — — EP claimed
EP-1422221-A1 Novel process for the preparation of 2-aminomethylpyridine derivative Bayer CropScience SA (FR) 2004-05-26 — — EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060100441-A1 Process for the preparation of 2-aminomethylpyridine derivative AZI2, CYP2C9, ABL2 TDP1 772/4885L3MBTL1 4605/4885ALDH1A1 482/4885
US-20060004206-A1 Novel process for the preparation of 2-aminomethylpyridine derivative AZI2, IL4I1, ABL2 TDP1 977/4885L3MBTL1 4751/4885ALDH1A1 579/4885
US-10781176-B2 Catalytic hydrogenation of substituted cyanopyridines and process for preparing substituted pyridylmethylbenzamides HCN4, PHYKPL, PYCR1 TDP1 1895/4885L3MBTL1 4826/4885ALDH1A1 3619/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.