Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TTR | P02766 | 1/20 | 0.35 |
| ▸ | IL2 | P60568 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11990336 | 0.92 | LMNA (0.42) | LMNAMEN1KMT2ACYP2C19CYP3A4 | |
| SCHEMBL20434503 | 0.85 | EPHX2 (0.40) | LMNAMEN1KMT2ACYP2C19CYP3A4 | |
| SCHEMBL19116591 | 0.84 | MEN1 (0.49) | LMNAMEN1KMT2ACYP2C19CYP3A4 | |
| SCHEMBL19116585 | 0.84 | MEN1 (0.49) | LMNAMEN1KMT2ACYP2C19CYP3A4 | |
| SCHEMBL14519321 | 0.83 | LMNA (0.38) | LMNAMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL26712776 | 0.81 | MAPT (0.41) | LMNAMEN1KMT2ASMN1; SMN2HSD17B10 | |
| SCHEMBL12377426 | 0.80 | CTH (0.35) | LMNAMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL11990499 | 0.79 | SMN1; SMN2 (0.53) | LMNAMEN1KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL24285353 | 0.79 | LMNA (0.43) | LMNAMEN1KMT2ACYP2C19SMN1; SMN2 | |
| SCHEMBL15044600 | 0.79 | SMN1; SMN2 (0.40) | LMNAMEN1KMT2ACYP2C19SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8729258-B2 | Luminescent macrocyclic lanthanide complexes | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2014-05-20 | — | — | US | disclosed |
| US-20120329174-A1 | LUMINESCENT MACROCYCLIC LANTHANIDE COMPLEXES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-12-27 | — | — | US | disclosed |
| US-8173800-B2 | Hydroxy-isophthalamide moieties; antibodies; high stability, luminescence; kits | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-05-08 | — | — | US | disclosed |
| US-20080213917-A1 | LUMINESCENT MACROCYCLIC LANTHANIDE COMPLEXES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2008-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080213917-A1 | LUMINESCENT MACROCYCLIC LANTHANIDE COMPLEXES | SSB, HACD3, CLTA | LMNA 2003/4885MEN1 1772/4885KMT2A 3655/4885 |
| US-20120329174-A1 | LUMINESCENT MACROCYCLIC LANTHANIDE COMPLEXES | SSB, HACD3, CLTA | LMNA 2003/4885MEN1 1772/4885KMT2A 3655/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.