Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.40 |
| ▸ | NPFFR2 | Q9Y5X5 | 3/20 | 0.40 |
| ▸ | IDO1 | P14902 | 2/20 | 0.38 |
| ▸ | KDR | P35968 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 2/20 | 0.35 |
| ▸ | ABL1 | P00519 | 1/20 | 0.35 |
| ▸ | BCR | P11274 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.35 |
| ▸ | HTR3B | O95264 | 1/20 | 0.35 |
| ▸ | HTR3A | P46098 | 1/20 | 0.35 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.35 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | NPFFR1 | Q9GZQ6 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1086197 | 0.69 | NPFFR2 (0.58) | HSD11B1NPFFR2IDO1KDRSLC6A3 | |
| SCHEMBL31144967 | 0.69 | NPFFR2 (0.58) | HSD11B1NPFFR2IDO1KDRSLC6A3 | |
| SCHEMBL10656533 | 0.69 | KDR (0.56) | HSD11B1NPFFR2IDO1KDRSLC6A3 | |
| SCHEMBL3530983 | 0.68 | KDR (0.53) | NPFFR2IDO1KDRSLC6A3ABL1 | |
| Hydrochloric Acid SCHEMBL4383135 | 0.68 | NPFFR2 (0.56) | HSD11B1NPFFR2IDO1KDRSLC6A3 | |
| Hydrochloric Acid SCHEMBL30536926 | 0.68 | NPFFR2 (0.56) | HSD11B1NPFFR2IDO1KDRSLC6A3 | |
| SCHEMBL2773936 | 0.68 | CCR2 (0.39) | NPFFR2IDO1KDRSLC6A3CCR2 | |
| SCHEMBL31542016 | 0.67 | KDR (0.54) | HSD11B1NPFFR2KDRSLC6A3HTR3E | |
| SCHEMBL1794695 | 0.67 | KDR (0.54) | HSD11B1NPFFR2KDRSLC6A3HTR3E | |
| SCHEMBL375961 | 0.67 | TSHR (0.59) | HSD11B1NPFFR2KDRSLC6A3HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6867207-B2 | IL-5 inhibiting 6-azauracil derivatives | JANSSEN PHARMACEUTICA N.V. (BE) | 2005-03-15 | — | — | US | disclosed |
| US-20020072603-A1 | Novel IL-5 inhibiting 6-azauracil derivatives | LACRAMPE JEAN FERNAND ARMAND (FR) | 2002-06-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020072603-A1 | Novel IL-5 inhibiting 6-azauracil derivatives | IL6ST, ALOX5, IL5 | HSD11B1 191/4885NPFFR2 1898/4885IDO1 743/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.