Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | NSD2 | O96028 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | APEX1 | P27695 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15331298 | 0.84 | LMNA (0.43) | LMNASMN1; SMN2NPSR1L3MBTL1GAA | |
| SCHEMBL16245851 | 0.83 | PKM (0.44) | LMNASMN1; SMN2L3MBTL1GAAMAPT | |
| SCHEMBL15330318 | 0.82 | LMNA (0.41) | LMNASMN1; SMN2NPSR1L3MBTL1GAA | |
| SCHEMBL10312521 | 0.79 | RAB9A (0.46) | LMNASMN1; SMN2NPSR1L3MBTL1MAPT | |
| SCHEMBL597464 | 0.76 | HCAR2 (0.43) | SMN1; SMN2MAPTCYP2C9HPGDNPC1 | |
| SCHEMBL3321542 | 0.76 | S1PR4 (0.52) | LMNASMN1; SMN2NPSR1L3MBTL1MAPT | |
| SCHEMBL1566534 | 0.76 | MAPK1 (0.54) | LMNASMN1; SMN2MAPTALDH1A1HPGD | |
| SCHEMBL2402900 | 0.75 | NOTUM (0.57) | L3MBTL1CCR1ALDH1A1NPC1RAB9A | |
| SCHEMBL8417127 | 0.75 | PKM (0.49) | LMNANPSR1L3MBTL1GAAALDH1A1 | |
| SCHEMBL1575018 | 0.75 | MAPK1 (0.61) | LMNASMN1; SMN2NPSR1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050234090-A1 | Modulators of chemokine receptor activity | PFIZER INC | 2005-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234090-A1 | Modulators of chemokine receptor activity | CCR3, CCR2, CCR1 | LMNA 3682/4885SMN1; SMN2 3260/4885NPSR1 291/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.