Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH2 | P05091 | 7/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16135585 | 0.90 | KMT2A (0.54) | ALDH2KMT2ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL9505080 | 0.87 | ALDH2 (0.59) | ALDH2KMT2ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL6255530 | 0.84 | ALDH2 (0.57) | ALDH2KMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL17577444 | 0.84 | ALDH2 (0.57) | ALDH2KMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL6362752 | 0.84 | KMT2A (0.60) | ALDH2KMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL26922366 | 0.84 | ALDH2 (0.57) | ALDH2KMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL16135736 | 0.83 | KDM4E (0.57) | ALDH2KMT2ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL21013836 | 0.83 | EPHX2 (0.55) | ALDH2KMT2AALDH1A1HPGDMEN1 | |
| SCHEMBL21196368 | 0.83 | ALDH2 (0.54) | ALDH2KMT2ASMN1; SMN2ALDH1A1HPGD | |
| SCHEMBL6358788 | 0.83 | ALDH1A1 (0.60) | ALDH2KMT2ASMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050009812-A1 | Remedies for stress diseases comprising mitochondrial benzodiazepine receptor antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-01-13 | — | — | US | claimed |
| EP-1438973-A1 | REMEDIES FOR STRESS DISEASES COMPRISING MITOCHONDRIAL BENZODIAZEPINE RECEPTOR ANTAGONISTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-07-21 | — | — | EP | claimed |
| US-9918474-B2 | Agents for combating plant pests | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2018-03-20 | — | — | US | disclosed |
| US-20170188582-A1 | Agents for Combating Plant Pests | BAYER AKTIENGESELLSCHAFT (DE) | 2017-07-06 | — | — | US | disclosed |
| US-9504254-B2 | Agents for combating plant pests | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-11-29 | — | — | US | disclosed |
| EP-2726460-B1 | COMPOUNDS FOR THE TREATMENT OF ADDICTION | GILEAD SCIENCES INC (US) | 2015-09-23 | — | — | EP | disclosed |
| US-20140107112-A1 | Agents for Combating Plant Pests | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2014-04-17 | — | — | US | disclosed |
| US-20120165374-A1 | AGENTS FOR CONTROLLING PLANT PESTS | BAYER CROPSCIENCE AG (DE) | 2012-06-28 | — | — | US | disclosed |
| US-20050009812-A1 | Remedies for stress diseases comprising mitochondrial benzodiazepine receptor antagonists | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-01-13 | — | — | US | disclosed |
| EP-1438973-A1 | REMEDIES FOR STRESS DISEASES COMPRISING MITOCHONDRIAL BENZODIAZEPINE RECEPTOR ANTAGONISTS | ONO PHARMACEUTICAL CO., LTD. (JP) | 2004-07-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120165374-A1 | AGENTS FOR CONTROLLING PLANT PESTS | DDT, ACHE, ERG28 | ALDH2 3400/4885KMT2A 1620/4885SMN1; SMN2 3647/4885 |
| US-20140107112-A1 | Agents for Combating Plant Pests | DDT, CYP51A1, AADAC | ALDH2 2847/4885KMT2A 1158/4885SMN1; SMN2 4618/4885 |
| US-20050009812-A1 | Remedies for stress diseases comprising mitochondrial benzodiazepine receptor antagonists | TFAM, CYP11B2, CYP11B1 | ALDH2 85/4885KMT2A 1711/4885SMN1; SMN2 972/4885 |
| US-20170188582-A1 | Agents for Combating Plant Pests | DDT, CYP51A1, AADAC | ALDH2 2847/4885KMT2A 1158/4885SMN1; SMN2 4618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.