SCHEMBL6357941

SCHEMBL6357941

OB(O)c1cccc(NC(=S)Nc2ccccc2)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.61
CYP3A4 P08684 2/20 0.61
TAS2R38 P59533 1/20 0.61
HSD17B10 Q99714 1/20 0.61
KMT2A Q03164 6/20 0.61
MEN1 O00255 4/20 0.59
KDM4E B2RXH2 1/20 0.59
MAPT P10636 4/20 0.54
GAA P10253 4/20 0.52
RAB9A P51151 2/20 0.52
NPC1 O15118 1/20 0.52
NOX1 Q9Y5S8 1/20 0.52
MAOA P21397 2/20 0.52
MAOB P27338 2/20 0.52
LMNA P02545 1/20 0.52
CYP1A2 P05177 2/20 0.50
CYP2C19 P33261 2/20 0.50
CYP2D6 P10635 1/20 0.49
CYP2C9 P11712 1/20 0.49
HTT P42858 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2554968 0.84 ALDH1A1 (0.57) ALDH1A1CYP3A4KMT2AMEN1KDM4E
SCHEMBL4072382 0.82 TP53 (0.61) HSD17B10KMT2AMEN1MAPTRAB9A
SCHEMBL2557259 0.80 MAPT (0.56) ALDH1A1KMT2AKDM4EMAPTGAA
SCHEMBL2559389 0.80 KDM4E (0.48) ALDH1A1KDM4EMAPTGAALMNA
SCHEMBL9010704 0.80 KMT2A (0.59) ALDH1A1TAS2R38HSD17B10KMT2AKDM4E
SCHEMBL13715294 0.80 TAS2R38 (0.53) ALDH1A1TAS2R38KMT2AKDM4EGAA
SCHEMBL132620 0.78 ALDH1A1 (1.00) ALDH1A1CYP3A4TAS2R38HSD17B10KMT2A
SCHEMBL2564353 0.78 TRPV1 (0.52) ALDH1A1KDM4EMGLL
SCHEMBL1557346 0.77 ALDH1A1 (0.60) ALDH1A1CYP3A4HSD17B10KMT2AMEN1
SCHEMBL3789938 0.76 KCNK3 (0.71) ALDH1A1KMT2AMEN1MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6919382-B2 Preparation and uses of conjugated solid supports for boronic acids THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) 2005-07-19 US disclosed
US-20030044840-A1 Preparation and uses of conjugated solid supports for boronic acids GOVERNORS OF THE UNIVERSITY OF ALBERTA, THE (CA) 2003-03-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030044840-A1 Preparation and uses of conjugated solid supports for boronic acids SLC43A1, SBDS, SLC7A5 ALDH1A1 1529/4885CYP3A4 2702/4885TAS2R38 3088/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.