Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | TYR | P14679 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.53 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | ESRRG | P62508 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13715294 | 0.85 | TAS2R38 (0.53) | KMT2ACYP1A2ALDH1A1TAS2R38ENPP2 | |
| SCHEMBL4047674 | 0.82 | KMT2A (0.76) | KMT2ACYP1A2ALDH1A1TP53TYR | |
| SCHEMBL1303751 | 0.81 | TRPV1 (0.51) | ALDH1A1ENPP2KDM4ETRPV1NLRP3 | |
| SCHEMBL10712920 | 0.81 | ENPP2 (0.47) | KMT2AALDH1A1ENPP2KDM4ETRPV1 | |
| SCHEMBL6357941 | 0.80 | ALDH1A1 (0.61) | KMT2ACYP1A2ALDH1A1TAS2R38HSD17B10 | |
| SCHEMBL2554968 | 0.79 | ALDH1A1 (0.57) | KMT2ACYP1A2ALDH1A1KDM4ETRPV1 | |
| SCHEMBL147446 | 0.77 | IDO1 (0.68) | KMT2ACYP1A2ALDH1A1TP53TYR | |
| SCHEMBL29838519 | 0.77 | IDO1 (0.68) | KMT2ACYP1A2ALDH1A1TP53TYR | |
| SCHEMBL2564353 | 0.76 | TRPV1 (0.52) | ALDH1A1ENPP2KDM4ETRPV1NLRP3 | |
| SCHEMBL2559389 | 0.75 | KDM4E (0.48) | ALDH1A1KDM4ETRPV1NLRP3IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0279307-B2 | Bifunctional chelating agents | ABBOTT LAB (US) | 1996-11-13 | — | — | EP | disclosed |
| EP-0315188-B1 | Methods and materials for the preparation of metal labelled antibody solutions | ABBOTT LAB (US) | 1994-06-01 | — | — | EP | disclosed |
| US-5245026-A | Radiopharmaceutical applications | ABBOTT LABORATORIES (US) | 1993-09-14 | — | — | US | disclosed |
| US-5227474-A | Complexing with radioactive metals, binding to biologically active molecules for treatment of tumors and diagnostic imaging | ABBOTT LABORATORIES (US) | 1993-07-13 | — | — | US | disclosed |
| EP-0308757-B1 | MULTIDENTATE CHELATORS BASED ON THE 8-HYDROXYQUINOLINE UNIT | ABBOTT LABORATORIES (US) | 1993-06-30 | — | — | EP | disclosed |
| US-5217704-A | Methods and materials for the preparation of metal labelled antibody solutions | ABBOTT LABORATORIES (US) | 1993-06-08 | — | — | US | disclosed |
| US-5130118-A | Radioactive metal ion labelled chelator | ABBOTT LABORATORIES (US) | 1992-07-14 | — | — | US | disclosed |
| US-5057302-A | Stable metal complexes of a substrate having a carboxymethyl arm of a polyaminopolycarboxylate framework; medical diagnosis; immunoassay; radiology; antitumor and anticarcinogenic agents | ABBOTT LABORATORIES (US) | 1991-10-15 | — | — | US | disclosed |
| US-5021567-A | Medical diagnosis; radiology; immunology; demetallization; stable complexes | ABBOTT LABORATORIES (US) | 1991-06-04 | — | — | US | disclosed |
| EP-0315188-A2 | Methods and materials for the preparation of metal labelled antibody solutions | ABBOTT LABORATORIES (US) | 1989-05-10 | — | — | EP | disclosed |
| EP-0308757-A1 | Multidentate chelators based on the 8-hydroxyquinoline unit | ABBOTT LABORATORIES (US) | 1989-03-29 | — | — | EP | disclosed |
| EP-0279307-A2 | Bifunctional chelating agents | ABBOTT LABORATORIES (US) | 1988-08-24 | — | — | EP | disclosed |