Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JUN | P05412 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.33 |
| ▸ | RELA | Q04206 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | XPO1 | O14980 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.30 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6417181 | 0.85 | JUN (0.32) | JUNNFKB1NFKB2RELA | |
| SCHEMBL6357961 | 0.84 | JUN (0.33) | JUNNFKB1NFKB2RELAALDH1A1 | |
| SCHEMBL832709 | 0.80 | ALDH1A1 (0.37) | JUNNFKB1NFKB2RELAALDH1A1 | |
| SCHEMBL2090729 | 0.80 | ALDH1A1 (0.49) | JUNNFKB1NFKB2RELAALDH1A1 | |
| SCHEMBL565623 | 0.79 | POLB (0.46) | JUNNFKB1NFKB2RELAALDH1A1 | |
| SCHEMBL31337111 | 0.78 | CA1 (0.35) | JUNNFKB1NFKB2RELAALDH1A1 | |
| SCHEMBL29021390 | 0.78 | CA1 (0.35) | JUNNFKB1NFKB2RELAALDH1A1 | |
| SCHEMBL6357726 | 0.76 | NFKB1 (0.40) | JUNNFKB1NFKB2RELAALDH1A1 | |
| SCHEMBL6357963 | 0.75 | XPO1 (0.33) | JUNNFKB1NFKB2RELAALDH1A1 | |
| SCHEMBL831077 | 0.75 | NOTUM (0.41) | JUNNFKB1NFKB2RELAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050176734-A1 | Method for producing 4-haloalkyl nicotinic acid amides | BAYER CROPSCIENCE AG (DE) | 2005-08-11 | — | — | US | disclosed |
| US-20040167334-A1 | Heterocyclic acylsulfimides, processes for their preparation, compositions comprising them and their use as pesticides | SHERMOLOVICH YURIY GRIGORIEVIC (UA) | 2004-08-26 | — | — | US | disclosed |
| US-20020032328-A1 | Heterocyclic acylsulfimides, processes for their preparation, compositions comprising them and their use as pesticides | AVENTIS CROPSCIENCE GMBH (DE) | 2002-03-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050176734-A1 | Method for producing 4-haloalkyl nicotinic acid amides | CBR3, CBR1, HCAR3 | JUN 2255/4885NFKB1 3506/4885NFKB2 3410/4885 |
| US-20020032328-A1 | Heterocyclic acylsulfimides, processes for their preparation, compositions comprising them and their use as pesticides | DDT, PTMS, TMT1A | JUN 4830/4885NFKB1 4262/4885NFKB2 4533/4885 |
| US-20040167334-A1 | Heterocyclic acylsulfimides, processes for their preparation, compositions comprising them and their use as pesticides | DDT, PTMS, TMT1A | JUN 4830/4885NFKB1 4262/4885NFKB2 4533/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.