Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 4/20 | 0.50 |
| ▸ | AKR1C1 | Q04828 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.49 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.46 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.46 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.45 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | PTGFR | P43088 | 2/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6357911 | 0.84 | MAP2K1 (0.43) | — | |
| SCHEMBL1307380 | 0.80 | AKR1C2 (0.64) | AKR1C2AKR1C1POLBAKR1C4AKR1C3 | |
| SCHEMBL1309186 | 0.73 | AKR1C2 (0.58) | AKR1C2AKR1C1POLBAKR1C4AKR1C3 | |
| SCHEMBL6347855 | 0.73 | AKR1C2 (0.72) | AKR1C2AKR1C1AKR1C4AKR1C3KCNK2 | |
| SCHEMBL1285766 | 0.72 | MLYCD (0.46) | TDP1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL6359829 | 0.71 | KCNK2 (0.57) | AKR1C2AKR1C1POLBAKR1C4AKR1C3 | |
| SCHEMBL1307972 | 0.71 | TP53 (0.70) | AKR1C2AKR1C1AKR1C4AKR1C3KCNK2 | |
| SCHEMBL1308286 | 0.70 | NPC1 (0.57) | AKR1C2AKR1C1POLBAKR1C4AKR1C3 | |
| SCHEMBL6359676 | 0.70 | AKR1C2 (0.55) | AKR1C2AKR1C1POLBAKR1C4AKR1C3 | |
| SCHEMBL17166275 | 0.70 | AKR1C2 (0.73) | AKR1C2AKR1C1POLBAKR1C4AKR1C3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | AKR1C2 3012/4885AKR1C1 2615/4885POLB 325/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.