SCHEMBL6358532

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1887532	0.83	LMNA (0.76)	GABBR2GABBR1LMNACYP1A2THRB
	SCHEMBL1881771	0.83	LMNA (0.76)	GABBR2GABBR1LMNACYP1A2THRB
	SCHEMBL1893272	0.83	LMNA (0.76)	GABBR2GABBR1LMNACYP1A2THRB
	SCHEMBL9417054	0.76	MEN1 (0.45)	GABBR2GABBR1LMNACYP1A2THRB
	SCHEMBL11085032	0.75	GABBR2 (0.62)	GABBR2GABBR1LMNACYP1A2THRB
	SCHEMBL2615283	0.72	GABBR2 (0.55)	GABBR2GABBR1AOC3
	SCHEMBL5230376	0.72	GABBR2 (0.59)	GABBR2GABBR1LMNACYP1A2THRB
	SCHEMBL2615282	0.72	GABBR2 (0.55)	GABBR2GABBR1AOC3
	SCHEMBL21616509	0.72	GABBR2 (0.46)	GABBR2GABBR1LMNACYP1A2THRB
	SCHEMBL9141278	0.71	GABBR2 (0.40)	GABBR2GABBR1LMNACYP1A2THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.