Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.65 |
| ▸ | MAPT | P10636 | 5/20 | 0.59 |
| ▸ | TP53 | P04637 | 3/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | RPA1 | P27694 | 2/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | AKR1C2 | P52895 | 4/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 4/20 | 0.44 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.44 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6359550 | 0.92 | MEN1 (0.66) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL6352333 | 0.89 | MEN1 (0.52) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL6352089 | 0.87 | TP53 (0.49) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL6352275 | 0.85 | AKR1C2 (0.53) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL6830522 | 0.83 | CA12 (0.44) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL6830007 | 0.82 | MEN1 (0.44) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL6353952 | 0.80 | MEN1 (0.55) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL6357909 | 0.80 | MAPT (0.55) | MEN1KMT2AALDH1A1KDM4EMAPT | |
| SCHEMBL6352347 | 0.79 | KCNK2 (0.60) | MEN1KMT2AALDH1A1MAPTAKR1C2 | |
| SCHEMBL6353520 | 0.79 | RPA1 (0.68) | MEN1KMT2AALDH1A1KDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | MEN1 3274/4885KMT2A 3645/4885ALDH1A1 462/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.