Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | TP53 | P04637 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | METAP2 | P50579 | 2/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6352089 | 0.89 | TP53 (0.49) | MAPTTP53KMT2AMEN1ALDH1A1 | |
| SCHEMBL6352275 | 0.86 | AKR1C2 (0.53) | MAPTTP53KMT2AMEN1ALDH1A1 | |
| SCHEMBL6359550 | 0.84 | MEN1 (0.66) | MAPTTP53KMT2AMEN1ALDH1A1 | |
| SCHEMBL6820401 | 0.80 | MAPT (0.58) | MAPTTP53KMT2AMEN1ALDH1A1 | |
| SCHEMBL6830007 | 0.80 | MEN1 (0.44) | MAPTTP53KMT2AMEN1ALDH1A1 | |
| SCHEMBL6358768 | 0.80 | MEN1 (0.65) | MAPTTP53KMT2AMEN1ALDH1A1 | |
| SCHEMBL6830522 | 0.79 | CA12 (0.44) | MAPTTP53KMT2AMEN1ALDH1A1 | |
| SCHEMBL6352333 | 0.78 | MEN1 (0.52) | MAPTTP53KMT2AMEN1ALDH1A1 | |
| SCHEMBL6352806 | 0.76 | MEN1 (0.61) | MAPTTP53KMT2AMEN1ALDH1A1 | |
| SCHEMBL6356961 | 0.76 | METAP2 (0.53) | KMT2AMEN1ALDH1A1METAP2PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | MAPT 4753/4885TP53 2308/4885KMT2A 3645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.