Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 3/20 | 0.53 |
| ▸ | AKR1C1 | Q04828 | 3/20 | 0.53 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.53 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.53 |
| ▸ | ALB | P02768 | 1/20 | 0.52 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.52 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.52 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | PPARD | Q03181 | 1/20 | 0.49 |
| ▸ | PPARA | Q07869 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6352089 | 0.90 | TP53 (0.49) | AKR1C2AKR1C1AKR1C4AKR1C3HDAC8 | |
| SCHEMBL6357909 | 0.86 | MAPT (0.55) | MEN1KMT2AHTTALDH1A1MAPT | |
| SCHEMBL6359550 | 0.85 | MEN1 (0.66) | AKR1C2AKR1C1AKR1C4AKR1C3MEN1 | |
| SCHEMBL6358768 | 0.85 | MEN1 (0.65) | AKR1C2AKR1C1AKR1C4AKR1C3MEN1 | |
| SCHEMBL6830007 | 0.83 | MEN1 (0.44) | AKR1C2AKR1C1AKR1C4AKR1C3ALB | |
| SCHEMBL6352333 | 0.82 | MEN1 (0.52) | AKR1C2AKR1C1AKR1C4AKR1C3MEN1 | |
| SCHEMBL6352806 | 0.80 | MEN1 (0.61) | AKR1C2AKR1C1AKR1C4AKR1C3MEN1 | |
| SCHEMBL6357674 | 0.79 | HDAC2 (0.56) | AKR1C2AKR1C1AKR1C4AKR1C3ALB | |
| SCHEMBL6358260 | 0.79 | AKR1C2 (0.70) | AKR1C2AKR1C1AKR1C4AKR1C3ALB | |
| SCHEMBL6830522 | 0.79 | CA12 (0.44) | AKR1C2AKR1C1AKR1C4AKR1C3MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | AKR1C2 3012/4885AKR1C1 2615/4885AKR1C4 3065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.