Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALB | P02768 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 5/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6358917 | 0.91 | ALB (0.54) | ALBALDH1A1LMNARXFP1HTT | |
| SCHEMBL6351777 | 0.78 | ALB (0.51) | ALBALDH1A1LMNAHTTMAPT | |
| SCHEMBL6360161 | 0.73 | SIRT2 (0.59) | ALBALDH1A1LMNAHTTMAPT | |
| SCHEMBL6913280 | 0.71 | SIRT2 (0.49) | MAPTSMN1; SMN2SIRT2 | |
| SCHEMBL6353746 | 0.70 | SIRT2 (0.61) | ALBALDH1A1LMNAHTTMAPT | |
| SCHEMBL6347994 | 0.70 | KCNK2 (0.52) | ALBALDH1A1HTTMAPTKDM4E | |
| SCHEMBL6708651 | 0.68 | SIRT2 (0.60) | ALDH1A1LMNAHTTMAPTNPC1 | |
| SCHEMBL15838844 | 0.68 | SIRT2 (0.75) | ALDH1A1LMNAMAPTNPC1SIRT2 | |
| SCHEMBL6349554 | 0.67 | AKR1C2 (0.48) | HTTKDM4ESIRT2MEN1KMT2A | |
| SCHEMBL6351360 | 0.67 | METAP2 (0.55) | LMNAHTTMAPTKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | ALB 1682/4885ALDH1A1 462/4885LMNA 4552/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.