Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK2 | O95069 | 1/20 | 0.52 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.52 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.52 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.52 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | ALB | P02768 | 1/20 | 0.47 |
| ▸ | ERO1A | Q96HE7 | 1/20 | 0.47 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.47 |
| ▸ | SIRT2 | Q8IXJ6 | 4/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6360161 | 0.91 | SIRT2 (0.59) | AKR1C4AKR1C3AKR1C2AKR1C1HTT | |
| SCHEMBL6351360 | 0.85 | METAP2 (0.55) | KCNK2KCNK10AKR1C2AKR1C1KDM4E | |
| SCHEMBL6349554 | 0.84 | AKR1C2 (0.48) | AKR1C4AKR1C3AKR1C2AKR1C1KDM4E | |
| SCHEMBL6358696 | 0.83 | SIRT2 (0.63) | KDM4EMAPK1HTTMEN1KMT2A | |
| SCHEMBL6358917 | 0.79 | ALB (0.54) | KDM4EHTTMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6357252 | 0.78 | SIRT2 (0.65) | AKR1C4AKR1C3AKR1C2AKR1C1HTT | |
| SCHEMBL13802485 | 0.77 | SERPINE1 (0.59) | KCNK2KCNK10AKR1C4AKR1C3AKR1C2 | |
| SCHEMBL6349003 | 0.77 | SIRT2 (0.49) | AKR1C4AKR1C3AKR1C2AKR1C1KDM4E | |
| SCHEMBL6711828 | 0.76 | SLC10A6 (0.52) | KDM4EMAPK1HTTSMN1; SMN2MAPT | |
| SCHEMBL6347687 | 0.76 | METAP2 (0.50) | AKR1C4AKR1C3AKR1C2AKR1C1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | KCNK2 4133/4885KCNK10 3271/4885AKR1C4 3065/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.