Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | CA7 | P43166 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL232646 | 0.82 | IRAK4 (0.47) | IRAK4CA12CA1CA2CA4 | |
| SCHEMBL2122337 | 0.78 | CA1 (0.39) | IRAK4CA12CA1CA2CA4 | |
| SCHEMBL789856 | 0.78 | KMT2A (0.36) | IRAK4CA12CA1CA2CA4 | |
| SCHEMBL6495128 | 0.76 | SCN4A (0.47) | KMT2AADRA2BSLC6A2MAOASLC6A4 | |
| SCHEMBL2008418 | 0.76 | CA1 (0.59) | IRAK4CA12CA1CA2CA4 | |
| SCHEMBL6784911 | 0.75 | ALDH1A1 (0.33) | IRAK4CA12CA1CA2CA4 | |
| SCHEMBL2117568 | 0.75 | MCHR1 (0.45) | KMT2AALDH1A1PTGS1LMNAKDM4E | |
| SCHEMBL19973199 | 0.74 | TSHR (0.52) | IRAK4CA12CA1CA2CA4 | |
| SCHEMBL7325155 | 0.74 | CA1 (0.39) | CA12CA1CA2CA4CA7 | |
| SCHEMBL17459933 | 0.74 | ALDH1A1 (0.54) | KMT2AALDH1A1TDP1GAASLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1060178-B1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF ROTAMASE ENZYMES | PFIZER (US) | 2003-09-03 | — | — | EP | claimed |
| US-6610707-B1 | Moderate neuronal regeneration and outgrowth and can be used for treating neurological disorders arising from neurodegenerative diseases and nerve damage. | PFIZER INC. | 2003-08-26 | — | — | US | claimed |
| EP-1060178-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF ROTAMASE ENZYMES | PFIZER INC. (US) | 2000-12-20 | — | — | EP | claimed |
| WO-1999045006-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF ROTAMASE ENZYMES | PFIZER INC. (US) | 1999-09-10 | — | — | WO | claimed |
| US-20120253038-A1 | PROCESSES FOR THE SYNTHESIS OF BAZEDOXIFENE ACETATE AND INTERMEDIATES THEREOF | SANDOZ AG (CH) | 2012-10-04 | — | — | US | disclosed |
| EP-2419406-A1 | PROCESSES FOR THE SYNTHESIS OF BAZEDOXIFENE ACETATE AND INTERMEDIATES THEREOF | Sandoz AG (CH) | 2012-02-22 | — | — | EP | disclosed |
| WO-2010118997-A1 | PROCESSES FOR THE SYNTHESIS OF BAZEDOXIFENE ACETATE AND INTERMEDIATES THEREOF | SANDOZ AG (CH) | 2010-10-21 | — | — | WO | disclosed |
| US-20080207898-A1 | PROCESSES FOR THE PREPARATION OF AMINOETHOXYBENZYL ALCOHOLS | WYETH (US) | 2008-08-28 | — | — | US | disclosed |
| US-20080207898-A1 | PROCESSES FOR THE PREPARATION OF AMINOETHOXYBENZYL ALCOHOLS | WYETH (US) | 2008-08-28 | — | — | US | disclosed |
| US-7375251-B2 | Processes for the preparation of aminoethoxybenzyl alcohols | WYETH (US) | 2008-05-20 | — | — | US | disclosed |
| US-7375251-B2 | Processes for the preparation of aminoethoxybenzyl alcohols | WYETH (US) | 2008-05-20 | — | — | US | disclosed |
| US-7375251-B2 | Processes for the preparation of aminoethoxybenzyl alcohols | WYETH (US) | 2008-05-20 | — | — | US | disclosed |
| WO-2006076350-A2 | PROCESSES FOR THE PREPARATION OF AMINOETHOXYBENZYL ALCOHOLS | WYETH (US) | 2006-07-20 | — | — | WO | disclosed |
| US-20060155147-A1 | Processes for the preparation of aminoethoxybenzyl alcohols | WYETH (US) | 2006-07-13 | — | — | US | disclosed |
| US-20060155147-A1 | Processes for the preparation of aminoethoxybenzyl alcohols | WYETH (US) | 2006-07-13 | — | — | US | disclosed |
| US-20060155147-A1 | Processes for the preparation of aminoethoxybenzyl alcohols | WYETH (US) | 2006-07-13 | — | — | US | disclosed |
| EP-1060178-B1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF ROTAMASE ENZYMES | PFIZER (US) | 2003-09-03 | — | — | EP | disclosed |
| US-6610707-B1 | Moderate neuronal regeneration and outgrowth and can be used for treating neurological disorders arising from neurodegenerative diseases and nerve damage. | PFIZER INC. | 2003-08-26 | — | — | US | disclosed |
| EP-1060178-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF ROTAMASE ENZYMES | PFIZER INC. (US) | 2000-12-20 | — | — | EP | disclosed |
| WO-1999045006-A1 | HETEROCYCLIC COMPOUNDS AS INHIBITORS OF ROTAMASE ENZYMES | PFIZER INC. (US) | 1999-09-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080207898-A1 | PROCESSES FOR THE PREPARATION OF AMINOETHOXYBENZYL ALCOHOLS | ADH1A, ADH1C, ADH5 | IRAK4 4751/4885CA12 3544/4885CA1 4260/4885 |
| US-20060155147-A1 | Processes for the preparation of aminoethoxybenzyl alcohols | ADH1A, ADH1C, ADH5 | IRAK4 4751/4885CA12 3544/4885CA1 4260/4885 |
| US-20120253038-A1 | PROCESSES FOR THE SYNTHESIS OF BAZEDOXIFENE ACETATE AND INTERMEDIATES THEREOF | CYP19A1, HSD17B11, CYP2F1 | IRAK4 4503/4885CA12 890/4885CA1 464/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.