Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.40 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.37 |
| ▸ | EP300 | Q09472 | 1/20 | 0.37 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.37 |
| ▸ | KAT8 | Q9H7Z6 | 1/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 3/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11054505 | 0.83 | HSD17B10 (0.41) | MMP2HSD17B10HPGDKDM4EALDH1A1 | |
| SCHEMBL29438133 | 0.82 | CA12 (0.50) | CSNK2A2CSNK2BCSNK2A1CSNK2A3MMP2 | |
| SCHEMBL17262955 | 0.82 | CA12 (0.50) | CSNK2A2CSNK2BCSNK2A1CSNK2A3MMP2 | |
| SCHEMBL2000711 | 0.80 | HSD17B10 (0.46) | HSD17B10HPGDKDM4EALDH1A1MAPT | |
| SCHEMBL206180 | 0.78 | DPP4 (0.47) | CSNK2A1MMP2HSD17B10HPGDKDM4E | |
| SCHEMBL30366773 | 0.77 | KDM4E (0.46) | HSD17B10HPGDKDM4EALDH1A1MAPT | |
| SCHEMBL10137909 | 0.77 | ERN1 (0.39) | MMP2ERN1 | |
| SCHEMBL10119565 | 0.75 | MMP2 (0.33) | MMP2IKBKB | |
| SCHEMBL744309 | 0.75 | CA12 (0.59) | HSD17B10HPGDKDM4EALDH1A1MAPT | |
| SCHEMBL17774953 | 0.75 | IKBKB (0.40) | HSD17B10HPGDKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050143366-A1 | Compounds for diagnosis, treatment and prevention of bone injury and metabolic disorders | UNIVERSITY OF LOUISVILLE RESEARCH FOUNDATION, INC. | 2005-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050143366-A1 | Compounds for diagnosis, treatment and prevention of bone injury and metabolic disorders | SOST, BMP2, BMP4 | CSNK2A2 4018/4885CSNK2B 4042/4885CSNK2A1 3889/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.