Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 7/20 | 0.64 |
| ▸ | RAB9A | P51151 | 7/20 | 0.62 |
| ▸ | NPC1 | O15118 | 6/20 | 0.62 |
| ▸ | CASP3 | P42574 | 1/20 | 0.62 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.62 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.61 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.61 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.61 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.61 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA2 | P00918 | 1/20 | 0.56 |
| ▸ | CA7 | P43166 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6359308 | 0.92 | SERPINE1 (0.68) | SERPINE1RAB9ANPC1CASP3SENP7 | |
| SCHEMBL6351306 | 0.85 | SERPINE1 (0.82) | SERPINE1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL6349319 | 0.84 | SERPINE1 (0.85) | SERPINE1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL6359691 | 0.81 | SERPINE1 (0.71) | SERPINE1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL6353650 | 0.80 | MEN1 (0.70) | SERPINE1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL420616 | 0.79 | SERPINE1 (1.00) | SERPINE1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL6358526 | 0.79 | SERPINE1 (0.67) | SERPINE1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL6357753 | 0.79 | SERPINE1 (0.67) | SERPINE1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL2274216 | 0.79 | RAB9A (0.60) | RAB9ANPC1CASP3SENP7PTGS2 | |
| SCHEMBL6349587 | 0.78 | NPC1 (0.64) | RAB9ANPC1CASP3SENP7AKR1C4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
| WO-2004018414-A2 | ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | SERPINE1 1929/4885RAB9A 3062/4885NPC1 3512/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.