Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.64 |
| ▸ | RAB9A | P51151 | 7/20 | 0.64 |
| ▸ | MEN1 | O00255 | 3/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.64 |
| ▸ | CASP3 | P42574 | 2/20 | 0.64 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.64 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.61 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.60 |
| ▸ | AKR1C1 | Q04828 | 2/20 | 0.60 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.60 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.60 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.56 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.56 |
| ▸ | RELA | Q04206 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6350714 | 0.91 | MAPT (0.65) | NPC1RAB9AMEN1KMT2ACASP3 | |
| SCHEMBL17166275 | 0.82 | AKR1C2 (0.73) | MEN1KMT2AAKR1C2AKR1C1AKR1C4 | |
| SCHEMBL6351992 | 0.82 | NPC1 (0.61) | NPC1RAB9AMEN1KMT2ACASP3 | |
| SCHEMBL6830367 | 0.79 | NPC1 (0.74) | NPC1RAB9AMEN1KMT2ASMN1; SMN2 | |
| SCHEMBL6359308 | 0.79 | SERPINE1 (0.68) | NPC1RAB9AMEN1KMT2ACASP3 | |
| SCHEMBL2272541 | 0.79 | PTGS2 (0.63) | NPC1RAB9AMEN1KMT2ACASP3 | |
| SCHEMBL6360688 | 0.78 | SERPINE1 (0.64) | NPC1RAB9AMEN1KMT2ACASP3 | |
| SCHEMBL6348852 | 0.78 | AKR1C2 (0.72) | RAB9AMEN1KMT2AAKR1C2AKR1C1 | |
| SCHEMBL6833148 | 0.78 | NPC1 (0.51) | NPC1RAB9AMEN1KMT2ACASP3 | |
| SCHEMBL2277756 | 0.77 | PTGS2 (0.57) | NPC1RAB9AMEN1KMT2ACASP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | PHARMACIA & UPJOHN COMPANY | 2004-06-10 | — | — | US | disclosed |
| WO-2004018428-A1 | ANTIBACTERIAL BENZOIC ACID DERIVATIVES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2004-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | NPC1 3512/4885RAB9A 3062/4885MEN1 3274/4885 |
| US-20040110802-A1 | Antibacterial benzoic acid derivatives | GABRD, GABBR1, GABRA1 | NPC1 3778/4885RAB9A 4337/4885MEN1 4132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.