Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RPA1 | P27694 | 2/20 | 0.50 |
| ▸ | METAP2 | P50579 | 1/20 | 0.47 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.46 |
| ▸ | SLC10A1 | Q14973 | 1/20 | 0.46 |
| ▸ | SLC10A6 | Q3KNW5 | 1/20 | 0.46 |
| ▸ | MIF | P14174 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ACLY | P53396 | 1/20 | 0.45 |
| ▸ | FABP4 | P15090 | 1/20 | 0.45 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.45 |
| ▸ | GPR27 | Q9NS67 | 2/20 | 0.45 |
| ▸ | WDR5 | P61964 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.44 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6352408 | 0.87 | NPC1 (0.55) | RPA1MIFMAPTMEN1KMT2A | |
| SCHEMBL6347755 | 0.84 | MIF (0.54) | RPA1METAP2SLC10A2SLC10A1SLC10A6 | |
| SCHEMBL6833646 | 0.83 | RPA1 (0.51) | RPA1METAP2SLC10A2SLC10A1SLC10A6 | |
| SCHEMBL6818512 | 0.83 | RPA1 (0.51) | RPA1METAP2SLC10A2SLC10A1SLC10A6 | |
| SCHEMBL6351997 | 0.73 | CPT2 (0.48) | MAPTMEN1KMT2ATP53 | |
| SCHEMBL6353713 | 0.72 | MAPT (0.55) | MAPTMEN1KMT2ATP53 | |
| SCHEMBL6346651 | 0.72 | METAP2 (0.65) | METAP2SLC10A2SLC10A1SLC10A6MIF | |
| SCHEMBL1307332 | 0.72 | PPARG (0.71) | METAP2ACLYMEN1KMT2AAKR1C2 | |
| SCHEMBL7209357 | 0.72 | SLC10A6 (0.76) | METAP2SLC10A2SLC10A1SLC10A6MAPT | |
| SCHEMBL6352359 | 0.72 | METAP2 (0.71) | RPA1METAP2SLC10A2SLC10A1SLC10A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | RPA1 3847/4885METAP2 1269/4885SLC10A2 2503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.