Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C2 | P52895 | 5/20 | 0.60 |
| ▸ | AKR1C1 | Q04828 | 5/20 | 0.60 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.58 |
| ▸ | AKR1C4 | P17516 | 2/20 | 0.57 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.57 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.56 |
| ▸ | PIM1 | P11309 | 1/20 | 0.56 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.56 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | ABL1 | P00519 | 2/20 | 0.56 |
| ▸ | RIN1 | Q13671 | 2/20 | 0.56 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.55 |
| ▸ | KCNK10 | P57789 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6349632 | 0.89 | CHEK1 (0.70) | AKR1C2AKR1C1GPR35AKR1C4AKR1C3 | |
| SCHEMBL6347855 | 0.85 | AKR1C2 (0.72) | AKR1C2AKR1C1AKR1C4AKR1C3ABL1 | |
| SCHEMBL6353191 | 0.84 | LMNA (0.60) | AKR1C2AKR1C1AKR1C4AKR1C3CHEK1 | |
| SCHEMBL15702354 | 0.84 | ABL1 (0.79) | AKR1C2AKR1C1AKR1C4AKR1C3CHEK1 | |
| SCHEMBL6351826 | 0.83 | CHEK1 (0.53) | AKR1C2AKR1C1GPR35AKR1C4AKR1C3 | |
| SCHEMBL6353682 | 0.82 | AKR1C2 (0.71) | AKR1C2AKR1C1LMNATDP1POLB | |
| SCHEMBL6349404 | 0.81 | LMNA (0.81) | AKR1C2AKR1C1AKR1C4AKR1C3CHEK1 | |
| SCHEMBL6349859 | 0.81 | MAPT (0.76) | AKR1C2AKR1C1GPR35AKR1C4AKR1C3 | |
| SCHEMBL17166275 | 0.80 | AKR1C2 (0.73) | AKR1C2AKR1C1AKR1C4AKR1C3ABL1 | |
| SCHEMBL6350824 | 0.80 | KCNK2 (0.62) | AKR1C2AKR1C1AKR1C4AKR1C3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | PHARMACIA & UPJOHN COMPANY | 2005-05-26 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050113450-A1 | Antibacterial agents | CLPP, SPOUT1, SAMHD1 | AKR1C2 3012/4885AKR1C1 2615/4885GPR35 4501/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.