Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 5/20 | 0.55 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3279004 | 0.84 | ALOX5 (0.60) | ALOX5RIPK1PTGS1PTGS2NPC1 | |
| SCHEMBL4445336 | 0.82 | ALOX5 (0.50) | ALOX5RIPK1PTGS1PTGS2NPC1 | |
| SCHEMBL11127626 | 0.80 | ALOX5 (0.56) | ALOX5RIPK1PTGS1PTGS2NPC1 | |
| SCHEMBL28812362 | 0.80 | LMNA (0.57) | NPC1RAB9ACA12CA9LMNA | |
| SCHEMBL6360909 | 0.79 | ALOX5 (0.51) | ALOX5RIPK1PTGS1PTGS2NPC1 | |
| SCHEMBL23805084 | 0.78 | ALOX5 (0.55) | ALOX5RIPK1PTGS1PTGS2NPC1 | |
| SCHEMBL6037547 | 0.78 | ALOX5 (0.56) | ALOX5RIPK1PTGS1PTGS2NPC1 | |
| SCHEMBL1436622 | 0.78 | ALOX5 (0.70) | ALOX5RIPK1PTGS1PTGS2NPC1 | |
| SCHEMBL628573 | 0.78 | RIPK1 (0.53) | ALOX5RIPK1PTGS1PTGS2NPC1 | |
| SCHEMBL7646415 | 0.77 | HSD11B1 (0.54) | ALOX5RIPK1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014647-A1 | Method and composition for determining resistance to an acetohydroxy-acid synthase inhibitor | BASF AKTIENGESELLSCHAFT (DE) | 2005-01-20 | — | — | US | claimed |
| US-20050014647-A1 | Method and composition for determining resistance to an acetohydroxy-acid synthase inhibitor | BASF AKTIENGESELLSCHAFT (DE) | 2005-01-20 | — | — | US | disclosed |
| EP-1417331-A2 | IMPROVED METHOD AND COMPOSITION FOR DETERMINING RESISTANCE TO AN ACETOHYDROXYACID SYNTHASE INHIBITOR | BASF AKTIENGESELLSCHAFT (DE) | 2004-05-12 | — | — | EP | disclosed |
| WO-2003014379-A2 | IMPROVED METHOD AND COMPOSITION FOR DETERMINING RESISTANCE TO AN ACETOHYDROXYACID SYNTHASE INHIBITOR | BASF AKTIENGESELLSCHAFT (DE) | 2003-02-20 | — | — | WO | disclosed |