Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.49 |
| ▸ | MAN2B1 | O00754 | 3/20 | 0.47 |
| ▸ | MAN2A1 | Q16706 | 3/20 | 0.46 |
| ▸ | MAN1B1 | Q9UKM7 | 3/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.44 |
| ▸ | ROCK1 | Q13464 | 3/20 | 0.44 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.44 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.44 |
| ▸ | PAK4 | O96013 | 1/20 | 0.44 |
| ▸ | PRKCG | P05129 | 1/20 | 0.44 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | PRKACA | P17612 | 1/20 | 0.44 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | AKT2 | P31751 | 1/20 | 0.44 |
| ▸ | CLK2 | P49760 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16481098 | 1.00 | RIPK1 (0.49) | RIPK1MAN2B1MAN2A1MAN1B1EPHX2 | |
| SCHEMBL6360986 | 1.00 | RIPK1 (0.49) | RIPK1MAN2B1MAN2A1MAN1B1EPHX2 | |
| SCHEMBL3177566 | 0.83 | LMNA (0.51) | RIPK1EPHX2MMEALDH1A1 | |
| SCHEMBL28527056 | 0.81 | EPHX2 (0.47) | RIPK1MAN2B1MAN2A1MAN1B1EPHX2 | |
| SCHEMBL11218953 | 0.80 | CCR3 (0.40) | RIPK1EPHX2RPS6KB1GPR88ALDH1A1 | |
| SCHEMBL321238 | 0.80 | KDM4E (0.47) | EPHX2GSK3BHTT | |
| SCHEMBL15637305 | 0.79 | MAN2A1 (0.49) | MAN2A1MAN1B1ROCK2ROCK1RPS6KB1 | |
| SCHEMBL21490940 | 0.79 | EPHX2 (0.48) | RIPK1MAN2B1MAN2A1MAN1B1EPHX2 | |
| SCHEMBL21490939 | 0.79 | EPHX2 (0.48) | RIPK1MAN2B1MAN2A1MAN1B1EPHX2 | |
| SCHEMBL25267822 | 0.79 | NPSR1 (0.48) | RIPK1MAN2B1GPR88SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6858591-B2 | Antibiotic AA 896 analogs | WYETH HOLDINGS CORPORATION (US) | 2005-02-22 | — | — | US | disclosed |
| US-20030087874-A1 | 2-amino-3-hydroxy-3-uridyl-propanoic acid ester derivatives | AMERICAN CYANAMID COMPANY | 2003-05-08 | — | — | US | disclosed |
| WO-2002086139-A1 | ANTIBIOTIC AA 896 ANALOGS | WYETH HOLDINGS CORPORATION (US) | 2002-10-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030087874-A1 | 2-amino-3-hydroxy-3-uridyl-propanoic acid ester derivatives | UMPS, METTL3, FPR3 | RIPK1 4457/4885MAN2B1 2706/4885MAN2A1 2669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.