Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CTSG | P08311 | 2/20 | 0.37 |
| ▸ | CTRB1 | P17538 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | SCN1A | P35498 | 1/20 | 0.36 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.36 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5962211 | 0.87 | MMP12 (0.42) | SMN1; SMN2TSHRHPGDKMT2AMEN1 | |
| SCHEMBL8202589 | 0.75 | ANPEP (0.36) | CYP3A4CYP2C19HPGDKMT2ASLC6A2 | |
| SCHEMBL6367353 | 0.70 | CYP2D6 (0.50) | SMN1; SMN2TP53TSHRHPGDKMT2A | |
| SCHEMBL8702956 | 0.69 | TP53 (0.47) | SMN1; SMN2CYP3A4CYP2C9CYP2C19TP53 | |
| SCHEMBL16673219 | 0.69 | PRKCA (0.50) | SMN1; SMN2CYP3A4CYP2C9CYP2C19TP53 | |
| SCHEMBL11303515 | 0.69 | TDP1 (0.45) | SMN1; SMN2TP53TSHRKMT2ASLC6A2 | |
| SCHEMBL16672589 | 0.68 | HPGD (0.51) | SMN1; SMN2TP53TSHRHPGDKMT2A | |
| SCHEMBL2454845 | 0.68 | TDP1 (0.44) | SMN1; SMN2TP53TSHRKMT2ASLC6A2 | |
| SCHEMBL16673087 | 0.67 | PRKCA (0.51) | SMN1; SMN2CYP3A4CYP2C9CYP2C19TP53 | |
| SCHEMBL21647766 | 0.67 | TSHR (0.45) | SMN1; SMN2CYP3A4CYP2C9CYP2C19TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1063232-B1 | Process for producing erythro-3-amino-2-hydroxybutyric acid derivatives | DAISO CO LTD (JP) | 2005-12-14 | — | — | EP | disclosed |
| EP-1464638-A1 | Process for producing erythro-3-amino-2-hydroxybutyric acid derivatives | DAISO CO., LTD. (JP) | 2004-10-06 | — | — | EP | disclosed |
| EP-1063232-A2 | Process for producing erythro-3-amino-2-hydroxybutyric acid derivatives | DAISO CO., LTD. (JP) | 2000-12-27 | — | — | EP | disclosed |