Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 2/20 | 0.36 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.36 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | ACP3 | P15309 | 1/20 | 0.35 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5962211 | 0.75 | MMP12 (0.42) | KMT2AMEN1ALDH1A1HPGDALOX5 | |
| SCHEMBL6367346 | 0.75 | SMN1; SMN2 (0.41) | KMT2AMEN1CYP2C19HPGDSLC6A2 | |
| SCHEMBL8030279 | 0.70 | ADRA2B (0.40) | KMT2AMEN1ALDH1A1HPGDSLC6A2 | |
| SCHEMBL27660875 | 0.70 | DPP4 (0.47) | ANPEPERAP1ERAP2KMT2AMEN1 | |
| SCHEMBL4323888 | 0.70 | CTSC (0.44) | ANPEPERAP1ERAP2ACP3SLC6A2 | |
| SCHEMBL817399 | 0.70 | ANPEP (0.43) | ANPEPERAP1ERAP2KMT2AACP3 | |
| SCHEMBL3997283 | 0.70 | CTSC (0.44) | ANPEPERAP1ERAP2ACP3SLC6A2 | |
| SCHEMBL817464 | 0.70 | ANPEP (0.43) | ANPEPERAP1ERAP2KMT2AACP3 | |
| SCHEMBL2163440 | 0.70 | CTSC (0.44) | ANPEPERAP1ERAP2ACP3SLC6A2 | |
| SCHEMBL3636524 | 0.68 | SIGMAR1 (0.45) | ANPEPERAP1ERAP2KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0970066-A1 | AMINOEPOXIDES FROM AMINOALDEHYDES AND IN-SITU FORMED HALOMETHYL ORGANOMETALLIC REAGENT | G.D. SEARLE & CO. (US) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998029401-A1 | AMINOEPOXIDES FROM AMINOALDEHYDES AND IN-SITU FORMED HALOMETHYL ORGANOMETALLIC REAGENT | G.D. SEARLE & CO. (US) | 1998-07-09 | — | — | WO | disclosed |