Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.40 |
| ▸ | OXTR | P30559 | 5/20 | 0.38 |
| ▸ | AVPR1A | P37288 | 5/20 | 0.38 |
| ▸ | GHSR | Q92847 | 4/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.36 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.36 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.36 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | LTB4R2 | Q9NPC1 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6367692 | 0.92 | OXTR (0.41) | PDK1OXTRAVPR1AGHSRPRKAB2 | |
| SCHEMBL4225416 | 0.91 | MEN1 (0.37) | OXTRAVPR1AGHSRNR1H4PRKAB2 | |
| SCHEMBL4233789 | 0.89 | AQP1 (0.43) | OXTRAVPR1AGHSRPRKAB2PRKAG1 | |
| SCHEMBL4224732 | 0.89 | OXTR (0.41) | OXTRAVPR1APRKAB2PRKAG1PRKAA2 | |
| SCHEMBL4220726 | 0.87 | OXTR (0.42) | OXTRAVPR1APRKAB2PRKAG1PRKAA2 | |
| SCHEMBL4231442 | 0.86 | PRKAB2 (0.41) | OXTRAVPR1AGHSRCHRM1PRKAB2 | |
| SCHEMBL4231349 | 0.86 | OXTR (0.38) | OXTRAVPR1AGHSRPTGER1TMEM97 | |
| SCHEMBL4229060 | 0.86 | OXTR (0.39) | PDK1OXTRAVPR1AGHSRPRKAB2 | |
| SCHEMBL6047928 | 0.85 | OXTR (0.37) | OXTRAVPR1AGHSRPRKAB2PRKAG1 | |
| SCHEMBL6367712 | 0.84 | TDP1 (0.41) | OXTRAVPR1AGHSRPTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050261347-A1 | Dihydrobenzofuranyl alkanamine derivatives and methods for using same | WYETH (US) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261347-A1 | Dihydrobenzofuranyl alkanamine derivatives and methods for using same | ADRA2A, HTR2A, ADRA1A | PDK1 2152/4885OXTR 186/4885AVPR1A 28/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.