Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 5/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 5/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6369532 | 0.84 | TMEM97 (0.43) | ADRA2AADRA2BADRA2CALDH1A1SIGMAR1 | |
| SCHEMBL4217069 | 0.84 | ADRA2A (0.52) | ADRA2AADRA2BADRA2CTSHRALDH1A1 | |
| SCHEMBL6375440 | 0.79 | HRH3 (0.43) | TSHRHRH3CA12CA1CA2 | |
| SCHEMBL4401199 | 0.75 | ADRA2A (0.45) | ADRA2AADRA2BADRA2CTSHR | |
| SCHEMBL9558829 | 0.70 | ADRA2A (0.46) | ADRA2AADRA2BADRA2CTSHR | |
| SCHEMBL11125378 | 0.69 | — | — | |
| SCHEMBL24533674 | 0.68 | — | — | |
| SCHEMBL2023829 | 0.67 | ADRA2A (0.50) | ADRA2AADRA2BADRA2CMAOA | |
| SCHEMBL9558509 | 0.66 | ADRA2A (0.43) | ADRA2AADRA2BADRA2CTSHRMAOA | |
| SCHEMBL6368496 | 0.66 | ADRA2A (0.42) | ADRA2AADRA2BADRA2CTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050119461-A1 | Novel receptor, and compounds which bind thereto | THE UNIVERSITY OF MELBOURNE | 2005-06-02 | — | — | US | disclosed |
| EP-1044194-A4 | RECEPTOR WITH AN AFFINITY FOR COMPOUNDS OF THE OXAZOLINE CLASS | UNIV MELBOURNE (AU) | 2002-01-09 | — | — | EP | disclosed |
| EP-1044194-A1 | RECEPTOR WITH AN AFFINITY FOR COMPOUNDS OF THE OXAZOLINE CLASS | THE UNIVERSITY OF MELBOURNE (AU) | 2000-10-18 | — | — | EP | disclosed |
| WO-1999024411-A1 | RECEPTOR WITH AN AFFINITY FOR COMPOUNDS OF THE OXAZOLINE CLASS | THE UNIVERSITY OF MELBOURNE (AU) | 1999-05-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119461-A1 | Novel receptor, and compounds which bind thereto | GPR27, GPR174, GPR52 | GFER 1216/4885ADRA2A 137/4885ADRA2B 98/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.