Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.33 |
| ▸ | NOS2 | P35228 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23889337 | 0.74 | ADRA2A (0.34) | HPGD | |
| SCHEMBL3966028 | 0.69 | NOS2 (0.32) | NOS3NOS2TSHR | |
| SCHEMBL13369836 | 0.68 | — | — | |
| SCHEMBL18661278 | 0.68 | — | — | |
| SCHEMBL13355549 | 0.65 | NOS3 (0.32) | NISCHNOS3NOS2 | |
| SCHEMBL13453320 | 0.65 | NISCH (0.32) | NISCHGLAHPGDTSHR | |
| SCHEMBL13621430 | 0.65 | NISCH (0.32) | NISCHGLAHPGDTSHR | |
| SCHEMBL13452964 | 0.65 | NOS3 (0.32) | NISCHNOS3NOS2 | |
| SCHEMBL10057749 | 0.65 | NOS3 (0.32) | NISCHNOS3NOS2 | |
| SCHEMBL13452968 | 0.65 | NISCH (0.32) | NISCHGLAHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050107608-A1 | Ligands for use in catalytic processes | EIDGENOSSISCHE TECHNISCHE HOCHSCHULE ZURICH ETHZ (CH) | 2005-05-19 | — | — | US | disclosed |
| EP-1448575-A1 | LIGANDS FOR USE IN CATALYTIC PROCESSES | Eidgenössische Technische Hochschule (ETH) Zürich (CH) | 2004-08-25 | — | — | EP | disclosed |
| WO-2003048175-A1 | LIGANDS FOR USE IN CATALYTIC PROCESSES | EIDGENÖSSISCHE TECHNISCHE HOCHSCHULE ZÜRICH ETHZ (CH) | 2003-06-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050107608-A1 | Ligands for use in catalytic processes | PNKP, ITPA, PLCG2 | NISCH 527/4885NOS3 4479/4885NOS2 4618/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.