SCHEMBL3966028

SCHEMBL3966028

CC1N=c2ccccc2=N1

nearest known ligand 0.32

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
NOS2 P35228 2/20 0.32
NOS3 P29474 1/20 0.31
HTR5A P47898 1/20 0.30
TSHR P16473 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6557836 0.69 MAP2K7 (0.31)
SCHEMBL10103686 0.69 TRPA1 (0.31)
SCHEMBL31522793 0.69 MAOA (0.31)
SCHEMBL28536794 0.69
SCHEMBL9555406 0.69 S100A4 (0.32) TSHR
SCHEMBL10111693 0.67
SCHEMBL12215976 0.65 GAA (0.40) TSHR
SCHEMBL14606215 0.65
SCHEMBL12978432 0.64 ACHE (0.39) TSHRACHE
SCHEMBL10872817 0.63 PIM1 (0.34) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230192695-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS UNIV ARIZONA STATE (US) 2023-06-22 US disclosed
US-20230192695-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS UNIV ARIZONA STATE (US) 2023-06-22 US disclosed
EP-3419971-B1 GLYCOSIDASE INHIBITORS ASCENEURON SA (CH) 2022-04-20 EP disclosed
US-20210024526-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS UNITED STATES DEPARTMENT OF ENERGY 2021-01-28 US disclosed
US-10851106-B2 Substituted benzo[4,5]imidazo[1,2-F]phenanthridines, dibenzo[I.K]benzo[4,5]imidazo[1,2-F]benzofurophenanthridines and dibenzo[I.K]benzo[4,5]imidazo[1,2-F]benzo[4,5]thienophenanthridines as thermally assisted delayed fluorescent materials ARIZONA BOARD OF REGENTS, ACTING FOR AND ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2020-12-01 US disclosed
US-20200071330-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS UNITED STATES DEPARTMENT OF ENERGY 2020-03-05 US disclosed
EP-3281936-B1 COMPOUND AND ORGANIC ELECTRONIC DEVICE USING THE SAME SHANGHAI NICHEM FINE CHEMICAL CO LTD (CN) 2019-10-09 EP disclosed
US-10392387-B2 Substituted benzo[4,5]imidazo[1,2-a]phenanthro[9,10-c][1,8]naphthyridines, benzo[4,5]imidazo[1,2-a]phenanthro[9,10-c][1,5]naphthyridines and dibenzo[f,h]benzo[4,5]imidazo[2,1-a]pyrazino[2,3-c]isoquinolines as thermally assisted delayed fluorescent materials ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2019-08-27 US disclosed
US-20170362211-A1 SMALL MOLECULE INHIBITORS OF FIBROSIS THE SCRIPPS RESEARCH INSTITUTE 2017-12-21 US disclosed
US-20170342102-A1 COMPOSITIONS AND METHODS FOR TREATING CNS DISORDERS SAGE THERAPEUTICS, INC. (US) 2017-11-30 US disclosed
WO-2017173358-A1 OXYSTEROLS AND METHODS OF USE THEREOF SAGE THERAPEUTICS, INC. (US) 2017-10-05 WO disclosed
US-20170247405-A1 OXYSTEROLS AND METHODS OF USE THEREOF SAGE THERAPEUTICS, INC. 2017-08-31 US disclosed
US-20170233433-A1 COMPOSITIONS AND METHODS FOR TREATING CNS DISORDERS SAGE THERAPEUTICS, INC. (US) 2017-08-17 US disclosed
CN-103568583-B Useless cartridge, ink-jet recording apparatus and useless black recovery method KYOCERA DOCUMENT SOLUTIONS INC (JP) 2015-10-07 CN disclosed
CN-103568583-A Ink jet recording device, waste ink tray, and waste ink collecting method using waste ink tray KYOCERA DOCUMENT SOLUTIONS INC 2014-02-12 CN disclosed
US-20120165335-A1 CDK INHIBITORS CURIS, INC. 2012-06-28 US disclosed
WO-2009035031-A1 PAINT FOR LIVESTOCK MAT AND FLOOR OF LIVESTOCK HOUSE IDEMITSU KOSAN CO., LTD. (JP) 2009-03-19 WO disclosed
US-20080138385-A1 Antibacterial Composition, Antibacterial Molding, Solution Containing Antibacterial Composition, Detergent, Surface of Tatami Mat and Tatami Mat IDEMITSU TECHNOFINE CO., LTD. (JP) 2008-06-12 US disclosed
US-20080053134-A1 Air Conditioner DAIKIN INDUSTRIES, LTD. (JP) 2008-03-06 US disclosed
EP-1840475-A1 AIR CONDITIONER Daikin Industries, Ltd. (JP) 2007-10-03 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210024526-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS TTPA, TTC14, AAAS NOS2 3525/4885NOS3 3486/4885HTR5A 629/4885
US-20080138385-A1 Antibacterial Composition, Antibacterial Molding, Solution Containing Antibacterial Composition, Detergent, Surface of Tatami Mat and Tatami Mat TPMT, KAT5, CARM1 NOS2 799/4885NOS3 671/4885HTR5A 4279/4885
US-20170233433-A1 COMPOSITIONS AND METHODS FOR TREATING CNS DISORDERS GRIN2B, AVPR1B, GRIN2A NOS2 1403/4885NOS3 1381/4885HTR5A 334/4885
US-20200071330-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS TTPA, TTC14, AAAS NOS2 3525/4885NOS3 3486/4885HTR5A 629/4885
US-20230192695-A1 THERMALLY ASSISTED DELAYED FLUORESCENT MATERIALS WITH TRIAD-TYPE MATERIALS TTPA, TTC14, AAAS NOS2 3525/4885NOS3 3486/4885HTR5A 629/4885
US-10851106-B2 Substituted benzo[4,5]imidazo[1,2-F]phenanthridines, dibenzo[I.K]benzo[4,5]imidazo[1,2-F]benzofurophenanthridines and dibenzo[I.K]benzo[4,5]imidazo[1,2-F]benzo[4,5]thienophenanthridines as thermally assisted delayed fluorescent materials KCNK4, TRPC4, TBRG4 NOS2 4637/4885NOS3 4690/4885HTR5A 53/4885
US-20120165335-A1 CDK INHIBITORS CDK3, CDK6, CDKL1 NOS2 4328/4885NOS3 4403/4885HTR5A 3703/4885
US-10392387-B2 Substituted benzo[4,5]imidazo[1,2-a]phenanthro[9,10-c][1,8]naphthyridines, benzo[4,5]imidazo[1,2-a]phenanthro[9,10-c][1,5]naphthyridines and dibenzo[f,h]benzo[4,5]imidazo[2,1-a]pyrazino[2,3-c]isoquinolines as thermally assisted delayed fluorescent materials NT5C, HTR3D, IK NOS2 3468/4885NOS3 3432/4885HTR5A 15/4885
US-20170247405-A1 OXYSTEROLS AND METHODS OF USE THEREOF NR1H3, NR1H2, HSD17B7 NOS2 522/4885NOS3 403/4885HTR5A 1012/4885
US-20170362211-A1 SMALL MOLECULE INHIBITORS OF FIBROSIS MMP1, COL2A1, MMP8 NOS2 819/4885NOS3 762/4885HTR5A 4801/4885
US-20170342102-A1 COMPOSITIONS AND METHODS FOR TREATING CNS DISORDERS GRIN2B, ADRA2B, ADRA1B NOS2 1428/4885NOS3 1534/4885HTR5A 432/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.