Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.49 |
| ▸ | METAP1 | P53582 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.45 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6373109 | 0.87 | NPC1 (0.58) | ALDH1A1SLC6A7METAP1NPC1RAB9A | |
| SCHEMBL6375649 | 0.87 | KMT2A (0.58) | ALDH1A1MAPK1SLC6A7L3MBTL1CHEK2 | |
| SCHEMBL7340640 | 0.80 | CSNK2A2 (0.54) | ALDH1A1MAPK1L3MBTL1KDM4EKMT2A | |
| SCHEMBL6374827 | 0.80 | HDAC3 (0.48) | ALDH1A1MAPK1SLC6A7L3MBTL1CHEK2 | |
| SCHEMBL6134818 | 0.76 | POLB (0.51) | ALDH1A1MAPK1KDM4ECSNK2A2CSNK2A1 | |
| SCHEMBL6427613 | 0.76 | CHEK2 (0.64) | ALDH1A1MAPK1SLC6A7L3MBTL1CHEK2 | |
| SCHEMBL6135547 | 0.75 | HRH3 (0.52) | L3MBTL1KMT2ACSNK2A2CSNK2A1CSNK2B | |
| SCHEMBL6132254 | 0.75 | KDM4E (0.47) | ALDH1A1KDM4EKMT2ACSNK2A2CSNK2A1 | |
| SCHEMBL17656010 | 0.75 | CSNK2A2 (0.69) | ALDH1A1KDM4ENPC1RAB9ACSNK2A2 | |
| SCHEMBL27527905 | 0.75 | CSNK2A2 (0.48) | ALDH1A1KDM4ECSNK2A2CSNK2A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050181988-A1 | Echinocandin cyclic peptide derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-08-18 | — | — | US | disclosed |
| WO-2003068807-A2 | ECHINOCANDIN CYCLIC PEPTIDE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-08-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050181988-A1 | Echinocandin cyclic peptide derivatives | NGLY1, ARG1, ERG28 | ALDH1A1 4014/4885MAPK1 1625/4885SLC6A7 3772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.