Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | AQP1 | P29972 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4596687 | 0.89 | CA1 (0.40) | ALDH1A1LMNAFFAR1 | |
| SCHEMBL4596601 | 0.88 | MEN1 (0.36) | PTGER1AQP1SIRT2GPBAR1CACNA1H | |
| SCHEMBL4231408 | 0.85 | AQP1 (0.40) | AQP1SIRT2GPBAR1ALDH1A1LMNA | |
| SCHEMBL4596670 | 0.85 | PRKAB2 (0.37) | AQP1SIRT2GPBAR1CACNA1HALDH1A1 | |
| SCHEMBL4595335 | 0.84 | GPBAR1 (0.36) | PTGER1AQP1GPBAR1CACNA1HALDH1A1 | |
| SCHEMBL6367712 | 0.84 | TDP1 (0.41) | PTGER1AQP1SIRT2ALDH1A1LMNA | |
| SCHEMBL4224652 | 0.84 | PRKAB2 (0.37) | ALDH1A1LMNASIGMAR1 | |
| SCHEMBL4233589 | 0.83 | AQP1 (0.38) | AQP1ALDH1A1LMNASIGMAR1 | |
| SCHEMBL4220797 | 0.82 | FABP4 (0.37) | ALDH1A1LMNASIGMAR1 | |
| SCHEMBL6373736 | 0.81 | AQP1 (0.46) | PTGER1AQP1GPBAR1CACNA1HALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050261347-A1 | Dihydrobenzofuranyl alkanamine derivatives and methods for using same | WYETH (US) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050261347-A1 | Dihydrobenzofuranyl alkanamine derivatives and methods for using same | ADRA2A, HTR2A, ADRA1A | PTGER1 513/4885AQP1 2290/4885SIRT2 1953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.