Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | FCER2 | P06734 | 1/20 | 0.34 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HPGDS | O60760 | 1/20 | 0.34 |
| ▸ | DHFR | P00374 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 2/20 | 0.33 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.33 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | LAP3 | P28838 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8768456 | 0.80 | ALDH1A1 (0.41) | FOLH1ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL8768447 | 0.80 | ALDH1A1 (0.41) | FOLH1ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL23298421 | 0.79 | FOLH1 (0.38) | MMP1FOLH1ALDH1A1MEN1LMNA | |
| SCHEMBL8373319 | 0.78 | ALDH1A1 (0.40) | FOLH1ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL17826032 | 0.76 | MAPT (0.44) | FOLH1ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL13637118 | 0.76 | MMP3 (0.44) | FOLH1ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL15834154 | 0.76 | MMP3 (0.44) | FOLH1ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL13185402 | 0.76 | MMP3 (0.44) | FOLH1ALDH1A1MEN1LMNAKMT2A | |
| SCHEMBL6507883 | 0.73 | BCHE (0.39) | ALDH1A1MEN1LMNAKMT2AHPGDS | |
| SCHEMBL7771103 | 0.73 | ALDH1A1 (0.42) | FOLH1ALDH1A1MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050187138-A1 | Peptide beta-strand mimics based on pyridinones, pyrazinones, pyridazinones, and triazinones | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA, A CALIFORNIA CORPORATION (US) | 2005-08-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050187138-A1 | Peptide beta-strand mimics based on pyridinones, pyrazinones, pyridazinones, and triazinones | IAPP, GLP1R, PAM | MMP1 4115/4885FOLH1 3268/4885ALDH1A1 4813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.