Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.55 |
| ▸ | ABAT | P80404 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 4/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | BLM | P54132 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | GMNN | O75496 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TYR | P14679 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31676929 | 0.97 | ESR1 (0.52) | ESR1ESR2ABATCA2KDM4E | |
| SCHEMBL760351 | 0.90 | IDO1 (0.55) | ESR1ESR2CA2NPC1CA12 | |
| Hydrochloric Acid SCHEMBL31475280 | 0.88 | IDO1 (0.53) | ESR1ESR2CA2NPC1CA12 | |
| SCHEMBL76073 | 0.88 | ACHE (0.59) | ESR1ESR2KDM4EALDH1A1BLM | |
| SCHEMBL10589402 | 0.85 | ESR1 (0.46) | ESR1ESR2ABATCA2KDM4E | |
| SCHEMBL8406865 | 0.82 | CALM1 (0.63) | ESR1ESR2NPC1MAPTRAB9A | |
| SCHEMBL8984986 | 0.82 | ESR1 (0.55) | ESR1ESR2ABATCA2KDM4E | |
| SCHEMBL20357502 | 0.79 | CYP2C19 (0.69) | ALDH1A1KMT2AMEN1LMNAMAPT | |
| SCHEMBL8585678 | 0.79 | CYP1A2 (0.52) | ESR1ESR2KMT2AMEN1NPC1 | |
| SCHEMBL45130 | 0.79 | ESR1 (0.41) | ESR1ESR2ABATCA2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110156835-B | Acyl phosphine oxide-4-hydroxyphenyl sulfonium salt-containing compound and preparation method and application thereof | 同济大学 | 2021-06-08 | — | — | CN | claimed |
| US-7351434-B2 | Therapeutic Gastrodia extracts | ACADEMIA SINICA (TW) | 2008-04-01 | — | — | US | claimed |
| US-20070237840-A1 | Administering bis(4-hydroxybenzyl)sulfide for therapy of Huntington's disease | ACADEMIA SINICA (TW) | 2007-10-11 | — | — | US | claimed |
| JP-8188570-A | — | — | None | — | — | JP | disclosed |
| US-20250352606-A1 | Pharmaceutical Composition for Promoting Neurogenesis and Method of Utilizing Gastrodia Elata Extract or Adenosine Analog for Promoting Neurogenesis | AXR PHARMA INC (TW) | 2025-11-20 | — | — | US | disclosed |
| US-20250152601-A1 | Compositions and Methods for the Treatment of Sexual Dysfunctions | THE JONATHAN HURT LIVING TRUST (US) | 2025-05-15 | — | — | US | disclosed |
| WO-2023249498-A1 | METHODS FOR MODIFYING MICROBES | LINCOLN UNIVERSITY (NZ) | 2023-12-28 | — | — | WO | disclosed |
| CN-112190570-B | Application of gastrodia tuber source derivative in preparing medicine for treating acute or chronic pain | 中国医学科学院药物研究所 | 2023-05-05 | — | — | CN | disclosed |
| CN-112190571-B | Application of gastrodia tuber source derivative in preparing medicine for treating inflammatory bowel disease | 中国医学科学院药物研究所 | 2023-05-05 | — | — | CN | disclosed |
| US-11324827-B2 | Multifunctionalized polyethylene glycol derivative and preparation method therefor | XIAMEN SINOPEG BIOTECH CO., LTD. (CN) | 2022-05-10 | — | — | US | disclosed |
| CN-112961085-B | LED excitable intramolecular sensitization type sulfonium salt compound and preparation method and application thereof | 同济大学 | 2022-02-01 | — | — | CN | disclosed |
| US-5152807-A | Discoloration inhibition | EXXON CHEMICAL PATENTS INC. (US) | 1992-10-06 | — | — | US | disclosed |
| EP-0428973-A1 | Mixtures of stabilisers for elastomers | CIBA-GEIGY AG (CH) | 1991-05-29 | — | — | EP | disclosed |
| EP-0391735-A1 | Fuel oil compositions | EXXON CHEMICAL PATENTS INC. (US) | 1990-10-10 | — | — | EP | disclosed |
| EP-0388236-A1 | Fuel oil compositions | EXXON CHEMICAL PATENTS INC. (US) | 1990-09-19 | — | — | EP | disclosed |
| EP-0385778-A1 | Fuel oil compositions | EXXON CHEMICAL PATENTS INC. (US) | 1990-09-05 | — | — | EP | disclosed |
| US-4298520-A | PHOSPHITES OR PHOSPHATES | ARGUS CHEMICAL CORP. (US) | 1981-11-03 | — | — | US | disclosed |
| US-4293472-A | O-ALKYLHYDROXYBENZYLPROPANE-1,3-DIOL ESTERS CONTAINING SULFIDE GROUPS | ADEKA ARGUS CHEMICAL CO., LTD. | 1981-10-06 | — | — | US | disclosed |
| US-4171298-A | SUBSTITUTED ORTHO-ALKYLHYDROXYBENZYLPROPANE-1,3-DIOL ESTERS | ARGUS CHEMICAL CORPORATION (US) | 1979-10-16 | — | — | US | disclosed |
| US-4025399-A | ELECTRICAL, RECORDING LAYER WITH A CONDUCTIVE AGENT, A LEUCO BASE AND A PHENOLIC RESIN | CANON KABUSHIKI KAISHA (JA) | 1977-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070237840-A1 | Administering bis(4-hydroxybenzyl)sulfide for therapy of Huntington's disease | HTT, SNCA, SLC2A4 | ESR1 3557/4885ESR2 2970/4885ABAT 42/4885 |
| US-11324827-B2 | Multifunctionalized polyethylene glycol derivative and preparation method therefor | HDGF, F11, F12 | ESR1 2621/4885ESR2 3232/4885ABAT 4359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.