Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 1/20 | 0.54 |
| ▸ | CDK4 | P11802 | 4/20 | 0.51 |
| ▸ | CCND1 | P24385 | 4/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | LTA4H | P09960 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6382619 | 0.82 | FFAR1 (0.51) | FFAR1PPARGCDK4CCND1MAPK1 | |
| SCHEMBL6486637 | 0.82 | LTA4H (0.47) | FFAR1PPARGPOLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL6486014 | 0.80 | MTNR1A (0.47) | POLBL3MBTL1RAB9ASMN1; SMN2LMNA | |
| SCHEMBL6381119 | 0.80 | NPC1 (0.49) | FFAR1PPARGPOLBL3MBTL1MAPK1 | |
| SCHEMBL4443382 | 0.78 | CDK4 (0.56) | FFAR1PPARGCDK4CCND1L3MBTL1 | |
| SCHEMBL6383877 | 0.78 | NR1H4 (0.56) | FFAR1PPARGPOLBMAPK1RAB9A | |
| SCHEMBL6379239 | 0.76 | SMN1; SMN2 (0.60) | FFAR1PPARGL3MBTL1MAPK1RAB9A | |
| SCHEMBL1608367 | 0.76 | ALDH1A1 (0.51) | POLBMAPK1SMN1; SMN2LMNAMAPT | |
| SCHEMBL27565238 | 0.76 | CDK4 (0.61) | CDK4CCND1MAPK1RAB9ASMN1; SMN2 | |
| SCHEMBL6380456 | 0.76 | PPARG (0.57) | FFAR1PPARGCDK4CCND1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050032787-A1 | Pheny (alkyl)carboxylic acid derivatives and dionic phenylalkylheterocyclic derivatives and their use as medicines with serum glucose and/or serum lipid lowering activity | SIGMA-TAU INDUSTRIES FARMACEUTICHE RIUNITE S.P.A. (IT) | 2005-02-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050032787-A1 | Pheny (alkyl)carboxylic acid derivatives and dionic phenylalkylheterocyclic derivatives and their use as medicines with serum glucose and/or serum lipid lowering activity | LIPC, CPT1A, GPR119 | FFAR1 63/4885PPARG 127/4885CDK4 4686/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.