Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | TOP2A | P11388 | 1/20 | 0.36 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6383727 | 0.90 | MEN1 (0.39) | MEN1KMT2AGAAGABRA1GABRB2 | |
| SCHEMBL6382626 | 0.86 | HTT (0.46) | MEN1KMT2AALDH1A1TSHRHTT | |
| SCHEMBL6387764 | 0.83 | ROCK2 (0.37) | MEN1KMT2AGAAALDH1A1LMNA | |
| SCHEMBL6382108 | 0.80 | MEN1 (0.38) | MEN1KMT2AGAAGABRA1GABRB2 | |
| SCHEMBL6658731 | 0.79 | DRD2 (0.35) | MEN1KMT2AALDH1A1MAPTGSK3B | |
| SCHEMBL6382649 | 0.76 | HTT (0.44) | KMT2AALDH1A1TSHRHTTKDM4E | |
| SCHEMBL6384389 | 0.75 | MEN1 (0.40) | MEN1KMT2AGAAGABRA1GABRB2 | |
| SCHEMBL6380404 | 0.71 | DHPS (0.43) | GAAALDH1A1LMNAKDM4EMAPT | |
| SCHEMBL6382724 | 0.71 | ROCK2 (0.36) | MEN1KMT2AGAAALDH1A1LMNA | |
| SCHEMBL6382631 | 0.70 | DRD2 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050251927-A9 | Dyeing composition comprising an acylaminophenol coupler and use of this coupler for dyeing keratinous fibres | VIDAL LAURENT | 2005-11-17 | — | — | US | claimed |
| US-20040205906-A1 | Dyeing composition comprising an acylaminophenol coupler and use of this coupler for dyeing keratinous fibres | L'OREAL S.A. (FR) | 2004-10-21 | — | — | US | claimed |
| EP-1438949-A1 | Composition for dyeing keratinous fibres comprising an acylaminophenol coupler | L'OREAL (FR) | 2004-07-21 | — | — | EP | claimed |
| US-20050251927-A9 | Dyeing composition comprising an acylaminophenol coupler and use of this coupler for dyeing keratinous fibres | VIDAL LAURENT | 2005-11-17 | — | — | US | disclosed |
| US-20040205906-A1 | Dyeing composition comprising an acylaminophenol coupler and use of this coupler for dyeing keratinous fibres | L'OREAL S.A. (FR) | 2004-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040205906-A1 | Dyeing composition comprising an acylaminophenol coupler and use of this coupler for dyeing keratinous fibres | KRT18, SLC25A20, ACR | MEN1 3299/4885KMT2A 763/4885GAA 4683/4885 |
| US-20050251927-A9 | Dyeing composition comprising an acylaminophenol coupler and use of this coupler for dyeing keratinous fibres | KRT18, SLC25A20, ACR | MEN1 3299/4885KMT2A 763/4885GAA 4683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.