Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | SRC | P12931 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6382680 | 0.87 | POLB (0.38) | DHPSPOLBCRBNNPC1RAB9A | |
| SCHEMBL6380807 | 0.84 | DHPS (0.41) | DHPSRAB9AMAPTKDM4EALDH1A1 | |
| SCHEMBL13135985 | 0.80 | DHPS (0.64) | DHPSNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL6662193 | 0.77 | DRD2 (0.47) | DHPSKDM4EP2RX7LMNADRD2 | |
| SCHEMBL6989799 | 0.76 | P2RX7 (0.40) | DHPSCRBNKDM4EALDH1A1P2RX7 | |
| SCHEMBL6383770 | 0.75 | HDAC3 (0.38) | POLBCRBNNPC1RAB9AMAPT | |
| SCHEMBL12597861 | 0.75 | CRBN (0.38) | DHPSPOLBCRBNNPC1RAB9A | |
| SCHEMBL6387764 | 0.74 | ROCK2 (0.37) | POLBNPC1RAB9AMAPTKDM4E | |
| SCHEMBL6384819 | 0.71 | MAPT (0.39) | POLBMAPTKDM4EALDH1A1GAA | |
| SCHEMBL6380414 | 0.71 | MEN1 (0.41) | MAPTKDM4EALDH1A1GAAHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050251927-A9 | Dyeing composition comprising an acylaminophenol coupler and use of this coupler for dyeing keratinous fibres | VIDAL LAURENT | 2005-11-17 | — | — | US | claimed |
| US-20040205906-A1 | Dyeing composition comprising an acylaminophenol coupler and use of this coupler for dyeing keratinous fibres | L'OREAL S.A. (FR) | 2004-10-21 | — | — | US | claimed |
| EP-1438949-A1 | Composition for dyeing keratinous fibres comprising an acylaminophenol coupler | L'OREAL (FR) | 2004-07-21 | — | — | EP | claimed |
| US-20050251927-A9 | Dyeing composition comprising an acylaminophenol coupler and use of this coupler for dyeing keratinous fibres | VIDAL LAURENT | 2005-11-17 | — | — | US | disclosed |
| US-20040205906-A1 | Dyeing composition comprising an acylaminophenol coupler and use of this coupler for dyeing keratinous fibres | L'OREAL S.A. (FR) | 2004-10-21 | — | — | US | disclosed |
| EP-1438949-A1 | Composition for dyeing keratinous fibres comprising an acylaminophenol coupler | L'OREAL (FR) | 2004-07-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040205906-A1 | Dyeing composition comprising an acylaminophenol coupler and use of this coupler for dyeing keratinous fibres | KRT18, SLC25A20, ACR | DHPS 408/4885POLB 1655/4885CRBN 2135/4885 |
| US-20050251927-A9 | Dyeing composition comprising an acylaminophenol coupler and use of this coupler for dyeing keratinous fibres | KRT18, SLC25A20, ACR | DHPS 408/4885POLB 1655/4885CRBN 2135/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.