Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHPS | P49366 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 7/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.37 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | DRD1 | P21728 | 1/20 | 0.36 |
| ▸ | DRD4 | P21917 | 1/20 | 0.36 |
| ▸ | DRD5 | P21918 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6384819 | 0.88 | MAPT (0.39) | HTTKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL6380404 | 0.84 | DHPS (0.43) | DHPSDRD2KDM4EALDH1A1MAPT | |
| SCHEMBL6662193 | 0.79 | DRD2 (0.47) | DHPSDRD2KDM4EP2RX7LMNA | |
| SCHEMBL6380842 | 0.77 | HDAC3 (0.41) | HTTKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL6382632 | 0.76 | CYP3A4 (0.38) | KDM4EALDH1A1MAPTHPGDLMNA | |
| SCHEMBL6382626 | 0.74 | HTT (0.46) | HTTKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL6382097 | 0.72 | MAPT (0.40) | HTTKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL6382680 | 0.71 | POLB (0.38) | DHPSKDM4EALDH1A1MAPTHPGD | |
| SCHEMBL28447107 | 0.70 | DRD2 (0.42) | DRD2P2RX7DRD1DRD4DRD5 | |
| SCHEMBL6989799 | 0.70 | P2RX7 (0.40) | DHPSDRD2KDM4EALDH1A1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050251927-A9 | Dyeing composition comprising an acylaminophenol coupler and use of this coupler for dyeing keratinous fibres | VIDAL LAURENT | 2005-11-17 | — | — | US | claimed |
| US-20040205906-A1 | Dyeing composition comprising an acylaminophenol coupler and use of this coupler for dyeing keratinous fibres | L'OREAL S.A. (FR) | 2004-10-21 | — | — | US | claimed |
| EP-1438949-A1 | Composition for dyeing keratinous fibres comprising an acylaminophenol coupler | L'OREAL (FR) | 2004-07-21 | — | — | EP | claimed |
| US-20050251927-A9 | Dyeing composition comprising an acylaminophenol coupler and use of this coupler for dyeing keratinous fibres | VIDAL LAURENT | 2005-11-17 | — | — | US | disclosed |
| US-20040205906-A1 | Dyeing composition comprising an acylaminophenol coupler and use of this coupler for dyeing keratinous fibres | L'OREAL S.A. (FR) | 2004-10-21 | — | — | US | disclosed |
| EP-1438949-A1 | Composition for dyeing keratinous fibres comprising an acylaminophenol coupler | L'OREAL (FR) | 2004-07-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040205906-A1 | Dyeing composition comprising an acylaminophenol coupler and use of this coupler for dyeing keratinous fibres | KRT18, SLC25A20, ACR | DHPS 408/4885DRD2 3651/4885HTT 1767/4885 |
| US-20050251927-A9 | Dyeing composition comprising an acylaminophenol coupler and use of this coupler for dyeing keratinous fibres | KRT18, SLC25A20, ACR | DHPS 408/4885DRD2 3651/4885HTT 1767/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.