Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | NQO2 | P16083 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PHPT1 | Q9NRX4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6382097 | 0.84 | MAPT (0.40) | KDM4EALDH1A1HPGDMAPTPOLB | |
| SCHEMBL6383770 | 0.78 | HDAC3 (0.38) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL6661841 | 0.77 | IDO1 (0.38) | PGRHDAC1LMNAPDK2PDK4 | |
| SCHEMBL6383712 | 0.75 | ROCK2 (0.36) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL6384389 | 0.71 | MEN1 (0.40) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL6380404 | 0.70 | DHPS (0.43) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL6382680 | 0.69 | POLB (0.38) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL4959475 | 0.68 | ALDH1A1 (0.59) | KDM4EALDH1A1HPGDHSD17B10GAA | |
| SCHEMBL10696147 | 0.68 | NQO2 (0.61) | KDM4EALDH1A1MAPTPOLBNPC1 | |
| SCHEMBL3150359 | 0.66 | PDK2 (0.52) | ALDH1A1MAPTPGRLMNAPDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050251927-A9 | Dyeing composition comprising an acylaminophenol coupler and use of this coupler for dyeing keratinous fibres | VIDAL LAURENT | 2005-11-17 | — | — | US | claimed |
| US-20040205906-A1 | Dyeing composition comprising an acylaminophenol coupler and use of this coupler for dyeing keratinous fibres | L'OREAL S.A. (FR) | 2004-10-21 | — | — | US | claimed |
| EP-1438949-A1 | Composition for dyeing keratinous fibres comprising an acylaminophenol coupler | L'OREAL (FR) | 2004-07-21 | — | — | EP | claimed |
| US-20050251927-A9 | Dyeing composition comprising an acylaminophenol coupler and use of this coupler for dyeing keratinous fibres | VIDAL LAURENT | 2005-11-17 | — | — | US | disclosed |
| US-20040205906-A1 | Dyeing composition comprising an acylaminophenol coupler and use of this coupler for dyeing keratinous fibres | L'OREAL S.A. (FR) | 2004-10-21 | — | — | US | disclosed |
| EP-1438949-A1 | Composition for dyeing keratinous fibres comprising an acylaminophenol coupler | L'OREAL (FR) | 2004-07-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040205906-A1 | Dyeing composition comprising an acylaminophenol coupler and use of this coupler for dyeing keratinous fibres | KRT18, SLC25A20, ACR | KDM4E 864/4885ALDH1A1 460/4885HPGD 1318/4885 |
| US-20050251927-A9 | Dyeing composition comprising an acylaminophenol coupler and use of this coupler for dyeing keratinous fibres | KRT18, SLC25A20, ACR | KDM4E 864/4885ALDH1A1 460/4885HPGD 1318/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.