Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.52 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.52 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.52 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.52 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | MMP14 | P50281 | 1/20 | 0.52 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6387882 | 0.87 | HTT (0.57) | HDAC2PRSS1TPSAB1EPHX1SMN1; SMN2 | |
| SCHEMBL31550495 | 0.78 | ALDH1A1 (0.62) | ALDH1A1PRSS1TPSAB1TPSD1TPSG1 | |
| SCHEMBL30440860 | 0.77 | ALDH1A1 (0.60) | ALDH1A1PRSS1TPSAB1TPSD1TPSG1 | |
| SCHEMBL8323868 | 0.77 | ALDH1A1 (0.60) | ALDH1A1PRSS1TPSAB1TPSD1TPSG1 | |
| SCHEMBL5873775 | 0.77 | ALDH1A1 (0.60) | ALDH1A1PRSS1TPSAB1TPSD1TPSG1 | |
| SCHEMBL8178335 | 0.77 | ALDH1A1 (0.60) | ALDH1A1PRSS1TPSAB1TPSD1TPSG1 | |
| SCHEMBL8149664 | 0.77 | PRSS1 (0.73) | ALDH1A1HDAC2PRSS1TPSAB1TPSD1 | |
| SCHEMBL8426731 | 0.77 | ALDH1A1 (0.60) | ALDH1A1PRSS1TPSAB1TPSD1TPSG1 | |
| SCHEMBL504661 | 0.77 | ALDH1A1 (0.60) | ALDH1A1PRSS1TPSAB1TPSD1TPSG1 | |
| SCHEMBL1722710 | 0.77 | ALDH1A1 (0.60) | ALDH1A1PRSS1TPSAB1TPSD1TPSG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050119305-A1 | Il-6 production inhibitors | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-06-02 | — | — | US | claimed |
| US-20050119305-A1 | Il-6 production inhibitors | ONO PHARMACEUTICAL CO., LTD. (JP) | 2005-06-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050119305-A1 | Il-6 production inhibitors | IL6, IL6ST, PADI6 | ALDH1A1 441/4885HDAC2 2783/4885PRSS1 1858/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.