Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PCK1 | P35558 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4616197 | 0.73 | PCK1 (0.38) | PCK1ALDH1A1KMT2APOLBKDM4E | |
| SCHEMBL4615986 | 0.69 | L3MBTL1 (0.50) | L3MBTL1ALDH1A1KMT2APOLBTSHR | |
| SCHEMBL4211228 | 0.68 | CA12 (0.50) | L3MBTL1ALDH1A1KMT2APOLBTSHR | |
| SCHEMBL13999451 | 0.67 | ALDH1A1 (0.55) | L3MBTL1ALDH1A1KMT2APOLBTSHR | |
| SCHEMBL7847724 | 0.67 | TYMP (0.55) | ALDH1A1KMT2AKDM4EMEN1LMNA | |
| SCHEMBL4613088 | 0.66 | KDM4E (0.52) | L3MBTL1ALDH1A1KMT2APOLBTSHR | |
| SCHEMBL10048444 | 0.66 | P2RX3 (0.56) | ALDH1A1KMT2APOLBKDM4EMEN1 | |
| SCHEMBL3985336 | 0.66 | L3MBTL1 (0.50) | PCK1L3MBTL1ALDH1A1KMT2APOLB | |
| SCHEMBL1073302 | 0.66 | TAAR1 (0.58) | — | |
| SCHEMBL4616203 | 0.65 | KDM4E (0.46) | PCK1L3MBTL1ALDH1A1KMT2APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1515972-A1 | AMIDE SUBSTITUTED XANTHINE DERIVATIVES WITH GLUCONEOGENESIS MODULATING ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 2005-03-23 | — | — | EP | disclosed |
| WO-2003106459-A1 | AMIDE SUBSTITUTED XANTHINE DERIVATIVES WITH GLUCONEOGENESIS MODULATING ACTIVITY | F. HOFFMANN-LA ROCHE AG (CH) | 2003-12-24 | — | — | WO | disclosed |