Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.30 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.30 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.30 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2489261 | 0.77 | HTR1A (0.34) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL1768148 | 0.77 | HTR1A (0.34) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL10265510 | 0.77 | PABPC1 (0.32) | — | |
| SCHEMBL6389818 | 0.77 | PABPC1 (0.36) | — | |
| SCHEMBL5430157 | 0.76 | — | — | |
| SCHEMBL8271289 | 0.76 | HTR1A (0.33) | HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL9408241 | 0.76 | — | — | |
| SCHEMBL25296735 | 0.75 | — | — | |
| SCHEMBL6388243 | 0.75 | PABPC1 (0.39) | — | |
| SCHEMBL13347183 | 0.75 | KDM4E (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2496578-A2 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS, SYNTHESIS THEREOF, AND METHODS OF USING SAME | University of Notre Dame du Lac (US) | 2012-09-12 | — | — | EP | claimed |
| US-20120220457-A1 | IMIDAZO [1,2-a]PYRIDINE COMPOUNDS, SYNTHESIS THEREOF, AND METHODS OF USING SAME | DOW AGROSCIENCES LLC (US) | 2012-08-30 | — | — | US | claimed |
| WO-2011057145-A2 | IMIDAZO[1,2-A] PYRIDINE COMPOUNDS, SYNTHESIS THEREOF, AND METHODS OF USING SAME | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2011-05-12 | — | — | WO | claimed |
| US-11820767-B2 | Benzyl amine-containing heterocyclic compounds and compositions useful against mycobacterial infection | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2023-11-21 | — | — | US | disclosed |
| US-11820767-B2 | Benzyl amine-containing heterocyclic compounds and compositions useful against mycobacterial infection | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2023-11-21 | — | — | US | disclosed |
| EP-2875029-B1 | 5,5-HETEROAROMATIC ANTI-INFECTIVE COMPOUNDS | MORASKI GARRETT (US) | 2021-11-10 | — | — | EP | disclosed |
| US-20210198254-A1 | BENZYL AMINE-CONTAINING HETEROCYCLIC COMPOUNDS AND COMPOSITIONS USEFUL AGAINST MYCOBACTERIAL INFECTION | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2021-07-01 | — | — | US | disclosed |
| US-10919888-B2 | Benzyl amine-containing heterocyclic compounds and compositions useful against mycobacterial infection | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2021-02-16 | — | — | US | disclosed |
| US-10913737-B2 | Imidazo [1,2-a]pyridine compounds, synthesis thereof, and methods of using same | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2021-02-09 | — | — | US | disclosed |
| US-20210009583-A1 | DEUTERATED IMIDAZOPYRIDINES | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2021-01-14 | — | — | US | disclosed |
| WO-2019175737-A1 | DEUTERATED IMIDAZOPYRIDINES | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2019-09-19 | — | — | WO | disclosed |
| US-20160318925-A1 | IMIDAZO [1,2-a]PYRIDINE COMPOUNDS, SYNTHESIS THEREOF, AND METHODS OF USING SAME | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2016-11-03 | — | — | US | disclosed |
| US-9309238-B2 | Imidazo [1,2-a]pyridine compounds, synthesis thereof, and methods of using same | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2016-04-12 | — | — | US | disclosed |
| US-20150210715-A1 | 5,5-HETEROAROMATIC ANTI-INFECTIVE COMPOUNDS | UNIVERSITY OF NOTRE DAME DU LAC | 2015-07-30 | — | — | US | disclosed |
| EP-2875029-A2 | 5,5-HETEROAROMATIC ANTI-INFECTIVE COMPOUNDS | Moraski, Garrett (US) | 2015-05-27 | — | — | EP | disclosed |
| WO-2014015167-A2 | 5,5-HETEROAROMATIC ANTI-INFECTIVE COMPOUNDS | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2014-01-23 | — | — | WO | disclosed |
| EP-2496578-A2 | IMIDAZO[1,2-A]PYRIDINE COMPOUNDS, SYNTHESIS THEREOF, AND METHODS OF USING SAME | University of Notre Dame du Lac (US) | 2012-09-12 | — | — | EP | disclosed |
| US-20120220457-A1 | IMIDAZO [1,2-a]PYRIDINE COMPOUNDS, SYNTHESIS THEREOF, AND METHODS OF USING SAME | DOW AGROSCIENCES LLC (US) | 2012-08-30 | — | — | US | disclosed |
| WO-2011057145-A2 | IMIDAZO[1,2-A] PYRIDINE COMPOUNDS, SYNTHESIS THEREOF, AND METHODS OF USING SAME | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2011-05-12 | — | — | WO | disclosed |
| US-20070173570-A1 | N-alkoxy-4, 4-dioxy-polyalkyl-piperidine compounds, with glycidyl or alkylcarbonyl groups as functional initiators for controlled radical polymerization | FUSO FRANCESCO | 2007-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11820767-B2 | Benzyl amine-containing heterocyclic compounds and compositions useful against mycobacterial infection | BET1, BRD4, BRD3 | HTR1A 4086/4885ADRA1D 3751/4885ADRA1A 3061/4885 |
| US-10913737-B2 | Imidazo [1,2-a]pyridine compounds, synthesis thereof, and methods of using same | RIF1, PYCR1, PNMT | HTR1A 1992/4885ADRA1D 989/4885ADRA1A 1814/4885 |
| US-20070173570-A1 | N-alkoxy-4, 4-dioxy-polyalkyl-piperidine compounds, with glycidyl or alkylcarbonyl groups as functional initiators for controlled radical polymerization | PTGER4, ALKBH3, PIGO | HTR1A 1859/4885ADRA1D 2074/4885ADRA1A 3056/4885 |
| US-20160318925-A1 | IMIDAZO [1,2-a]PYRIDINE COMPOUNDS, SYNTHESIS THEREOF, AND METHODS OF USING SAME | RIF1, PYCR1, PNMT | HTR1A 1992/4885ADRA1D 989/4885ADRA1A 1814/4885 |
| US-20120220457-A1 | IMIDAZO [1,2-a]PYRIDINE COMPOUNDS, SYNTHESIS THEREOF, AND METHODS OF USING SAME | RIF1, PYCR1, PNMT | HTR1A 1992/4885ADRA1D 989/4885ADRA1A 1814/4885 |
| US-20210009583-A1 | DEUTERATED IMIDAZOPYRIDINES | SDHA, PDF, IDH2 | HTR1A 4136/4885ADRA1D 1266/4885ADRA1A 2276/4885 |
| US-10919888-B2 | Benzyl amine-containing heterocyclic compounds and compositions useful against mycobacterial infection | BET1, BRD4, BRD3 | HTR1A 4086/4885ADRA1D 3751/4885ADRA1A 3061/4885 |
| US-20210198254-A1 | BENZYL AMINE-CONTAINING HETEROCYCLIC COMPOUNDS AND COMPOSITIONS USEFUL AGAINST MYCOBACTERIAL INFECTION | BET1, BRD4, BRD3 | HTR1A 4086/4885ADRA1D 3751/4885ADRA1A 3061/4885 |
| US-20150210715-A1 | 5,5-HETEROAROMATIC ANTI-INFECTIVE COMPOUNDS | API5, CASP5, IL5 | HTR1A 2842/4885ADRA1D 2313/4885ADRA1A 2022/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.