Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.56 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | POLA1 | P09884 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.38 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | PNP | P00491 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Ribose (Furanose) SCHEMBL639319 | 0.80 | HSP90AB1 (0.40) | DPP4HSP90AB1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL9351658 | 0.79 | CYP1A2 (0.51) | DPP4HSP90AB1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL29728815 | 0.79 | PDPK1 (0.59) | DPP4HSP90AB1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL258583 | 0.79 | PDPK1 (0.59) | DPP4HSP90AB1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL31527929 | 0.79 | CYP1A2 (0.51) | DPP4HSP90AB1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL30834788 | 0.77 | CYP1A2 (0.50) | DPP4HSP90AB1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL31012324 | 0.76 | CYP2C19 (0.63) | HSP90AB1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL546891 | 0.76 | CYP1A2 (0.49) | DPP4HSP90AB1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL17372399 | 0.76 | CYP2C19 (0.63) | HSP90AB1CYP1A2CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL5998452 | 0.76 | ADORA3 (0.55) | DPP4HSP90AB1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10662194-B2 | Substituted 6-anilino-9-heterocyclylpurine derivatives for inhibition of plant stress | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2020-05-26 | — | — | US | disclosed |
| EP-3233860-B1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | UNIV PALACKEHO (CZ) | 2020-01-29 | — | — | EP | disclosed |
| US-20170342072-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2017-11-30 | — | — | US | disclosed |
| EP-3233860-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | Univerzita Palackého V Olomouci (CZ) | 2017-10-25 | — | — | EP | disclosed |
| WO-2016095881-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2016-06-23 | — | — | WO | disclosed |
| EP-2430036-B1 | SUBSTITUTED 6-(BENZYLAMINO) PURINE RIBOSIDE DERIVATIVES, USE THEREOF AND COMPOSITIONS CONTAINING THESE DERIVATIVES | Univerzita Palackého v Olomouci (CZ) | 2014-07-30 | — | — | EP | disclosed |
| US-20140066394-A1 | Substituted 6-(Benzylamino) Purine Riboside Derivatives, Use Thereof and Compositions Containing These Derivatives | BIOPATTERNS, S.R.O (CZ) | 2014-03-06 | — | — | US | disclosed |
| EP-2173173-B1 | SUBSTITUTED 6-ANILINOPURINE DERIVATIVES AS INHIBITORS OF CYTOKININ OXIDASE/DEHYDROGENASE AND PREPARATIONS CONTAINING THESE DERIVATIVES | UNIV PALACKEHO (CZ) | 2013-07-24 | — | — | EP | disclosed |
| US-8222260-B2 | Substituted 6-anilinopurine derivatives as inhibitors of cytokinin oxidase/dehydrogenase and preparations containing these derivatives | Univerzita Palackego V Olomouci (CZ) | 2012-07-17 | — | — | US | disclosed |
| US-20120071433-A1 | Substituted 6-(Benzylamino) Purine Riboside Derivatives, Use Thereof and Compositions Containing These Derivatives | UNIVERZITA PALACKEHO V OLOMOUCI (CZ) | 2012-03-22 | — | — | US | disclosed |
| EP-1097939-B1 | Method for the synthesis of isoguanosine and of its 2'-derivatives | BAYER AG (US) | 2004-02-11 | — | — | EP | disclosed |
| EP-0778898-B1 | REDUCTION OF NONSPECIFIC HYBRIDIZATION BY USING NOVEL BASE-PAIRING SCHEMES | BAYER AG (US) | 2002-11-13 | — | — | EP | disclosed |
| US-20010026918-A1 | Reduction of nonspecific hybridization by using novel base-pairing schemes | COLLINS MARK L (US) | 2001-10-04 | — | — | US | disclosed |
| US-6232462-B1 | SYNTHESIS OF AN ISOGUANOSINE DERIVATIVE USED AS ANTISENSE AND APTAMER THERAPEUTICS AND DRUG DISCOVERY | BAYER CORPORATION | 2001-05-15 | — | — | US | disclosed |
| EP-1097939-A2 | Method for the synthesis of isoguanosine and its 2'-derivatives | Bayer Corporation (US) | 2001-05-09 | — | — | EP | disclosed |
| US-5780610-A | OLIGONUCLEOTIDE APTAMERS INCLUDING COMPLEMENTARY NONNATURAL NUCLEOTIDE UNITS | SIEMENS HEALTHCARE DIAGNOSTICS INC. | 1998-07-14 | — | — | US | disclosed |
| US-5681702-A | MINIMIZES BACKGROUND NOISE | CHIRON CORPORATION (US) | 1997-10-28 | — | — | US | disclosed |
| EP-0778898-A1 | REDUCTION OF NONSPECIFIC HYBRIDIZATION BY USING NOVEL BASE-PAIRING SCHEMES | CHIRON CORPORATION (US) | 1997-06-18 | — | — | EP | disclosed |
| WO-1996006950-A9 | REDUCTION OF NONSPECIFIC HYBRIDIZATION BY USING NOVEL BASE-PAIRING SCHEMES | — | 1997-05-09 | — | — | WO | disclosed |
| WO-1996006950-A1 | REDUCTION OF NONSPECIFIC HYBRIDIZATION BY USING NOVEL BASE-PAIRING SCHEMES | CHIRON CORPORATION (US) | 1996-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140066394-A1 | Substituted 6-(Benzylamino) Purine Riboside Derivatives, Use Thereof and Compositions Containing These Derivatives | PNP, NUDT1, TYMP | DPP4 1632/4885HSP90AB1 1296/4885CYP1A2 4184/4885 |
| US-20120071433-A1 | Substituted 6-(Benzylamino) Purine Riboside Derivatives, Use Thereof and Compositions Containing These Derivatives | CD38, NUDT1, PNP | DPP4 1464/4885HSP90AB1 1468/4885CYP1A2 4208/4885 |
| US-10662194-B2 | Substituted 6-anilino-9-heterocyclylpurine derivatives for inhibition of plant stress | TPMT, MTAP, ATIC | DPP4 3914/4885HSP90AB1 827/4885CYP1A2 220/4885 |
| US-20010026918-A1 | Reduction of nonspecific hybridization by using novel base-pairing schemes | UNG, SAMHD1, RNGTT | DPP4 1673/4885HSP90AB1 1214/4885CYP1A2 3279/4885 |
| US-20170342072-A1 | SUBSTITUTED 6-ANILINO-9-HETEROCYCLYLPURINE DERIVATIVES FOR INHIBITION OF PLANT STRESS | TPMT, MTAP, ATIC | DPP4 3914/4885HSP90AB1 827/4885CYP1A2 220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.