SCHEMBL6399073

SCHEMBL6399073

S[C@H]1CCN(Cc2ccccn2)C1

nearest known ligand 0.56

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 1/20 0.56
SIGMAR1 Q99720 2/20 0.54
LMNA P02545 1/20 0.53
CYP2C19 P33261 3/20 0.51
CYP1A2 P05177 2/20 0.51
KMT2A Q03164 1/20 0.51
KDM4E B2RXH2 3/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
TRPV6 Q9H1D0 1/20 0.49
CYP2D6 P10635 2/20 0.49
CYP3A4 P08684 1/20 0.49
POLB P06746 2/20 0.46
ALDH1A1 P00352 2/20 0.46
NPSR1 Q6W5P4 1/20 0.46
DRD4 P21917 1/20 0.44
PDE2A O00408 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6397656 1.00 L3MBTL1 (0.56) L3MBTL1SIGMAR1LMNACYP2C19CYP1A2
SCHEMBL938062 0.83 L3MBTL1 (0.57) L3MBTL1SIGMAR1LMNACYP2C19CYP1A2
SCHEMBL31653494 0.83 L3MBTL1 (0.57) L3MBTL1SIGMAR1LMNACYP2C19CYP1A2
SCHEMBL14197754 0.81 LMNA (0.60) L3MBTL1SIGMAR1LMNACYP2C19CYP1A2
SCHEMBL2033541 0.81 L3MBTL1 (0.56) L3MBTL1SIGMAR1LMNACYP2C19CYP1A2
SCHEMBL6397064 0.81 L3MBTL1 (0.59) L3MBTL1SIGMAR1LMNACYP2C19CYP1A2
Hydrochloric Acid SCHEMBL2033089 0.80 L3MBTL1 (0.58) L3MBTL1SIGMAR1LMNACYP2C19CYP1A2
SCHEMBL28270135 0.80 TRPV6 (0.65) L3MBTL1SIGMAR1LMNACYP2C19CYP1A2
SCHEMBL23507367 0.78 CXCR3 (0.55) L3MBTL1SIGMAR1LMNACYP2C19CYP1A2
SCHEMBL9976600 0.78 LMNA (0.53) L3MBTL1SIGMAR1LMNACYP2C19CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050004092-A1 Penem derivatives and antimicrobial agent containing the same DAIICHI SUNTORY PHARMA CO., LTD. (JP) 2005-01-06 US disclosed
EP-0757051-B1 PENEM DERIVATIVES AND ANTIMICROBIAL AGENT CONTAINING THE SAME DAIICHI SUNTORY PHARMA CO LTD (JP) 2003-10-29 EP disclosed
EP-0757051-A1 PENEM DERIVATIVES AND ANTIMICROBIAL AGENT CONTAINING THE SAME SUNTORY LIMITED (JP) 1997-02-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050004092-A1 Penem derivatives and antimicrobial agent containing the same MRPL21, MRPS2, MRPS28 L3MBTL1 580/4885SIGMAR1 235/4885LMNA 3637/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.