Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | CDK4 | P11802 | 1/20 | 0.37 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.35 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.35 |
| ▸ | RAD52 | P43351 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.33 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29353912 | 0.90 | MAPT (0.38) | MAPTHTTLMNAGAAMAPK10 | |
| SCHEMBL769388 | 0.90 | MAPT (0.38) | MAPTHTTLMNAGAAMAPK10 | |
| SCHEMBL21752509 | 0.84 | ADRB2 (0.40) | MAPTHTTLMNACDK4ADRB2 | |
| SCHEMBL14370143 | 0.84 | ADRB2 (0.40) | MAPTLMNAADRB2ADRB1MEN1 | |
| SCHEMBL7896079 | 0.81 | NR2E1 (0.43) | MAPTLMNAGAAMAPK10ADRB2 | |
| SCHEMBL3833773 | 0.80 | LMNA (0.40) | MAPTHTTLMNAMAPK10CDK4 | |
| SCHEMBL18979221 | 0.79 | LMNA (0.40) | MAPTLMNAGAAMAPK10CNR1 | |
| SCHEMBL6450928 | 0.79 | PLA2G4B (0.40) | MAPTHTTLMNAGAAMAPK10 | |
| SCHEMBL787012 | 0.79 | ADRB2 (0.44) | MAPTLMNAADRB2ADRB1MEN1 | |
| SCHEMBL29356358 | 0.79 | ADRB2 (0.44) | MAPTLMNAADRB2ADRB1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050065166-A1 | Substituted pyrimidines | BAYER CROPSCIENCE AG (DE) | 2005-03-24 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050065166-A1 | Substituted pyrimidines | DPYD, DHFR, TYMP | MAPT 4240/4885HTT 2216/4885LMNA 4169/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.