Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 6/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 6/20 | 0.34 |
| ▸ | SCN5A | Q14524 | 5/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.34 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4679278 | 0.76 | IGF1R (0.37) | SMN1; SMN2 | |
| SCHEMBL6446487 | 0.72 | GAA (0.36) | SCN1ASCN8ASCN5AGAASMN1; SMN2 | |
| SCHEMBL6400853 | 0.61 | GAA (0.30) | GAASMN1; SMN2 | |
| SCHEMBL29949208 | 0.60 | BACE1 (0.35) | SCN1ASCN8ASCN5ASMN1; SMN2 | |
| SCHEMBL20558244 | 0.59 | APLNR (0.56) | CLK4 | |
| SCHEMBL10517118 | 0.59 | ATM (0.36) | GAASMN1; SMN2 | |
| SCHEMBL5803747 | 0.59 | — | — | |
| SCHEMBL4826043 | 0.59 | — | — | |
| SCHEMBL5774132 | 0.58 | KMO (0.36) | — | |
| Hydrochloric Acid SCHEMBL14743836 | 0.57 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050014806-A1 | Substituted isoxazoles and their use as antibiotics | LABORATORIOS S.A.L.V.A.T., S.A. (ES) | 2005-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014806-A1 | Substituted isoxazoles and their use as antibiotics | XDH, SCO2, HAX1 | SCN1A 1417/4885SCN8A 3243/4885SCN5A 2427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.