Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6401561 | 1.00 | CYP1A2 (0.47) | CYP1A2ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL28742862 | 0.87 | MEN1 (0.47) | ALDH1A1KDM4EMAPTLMNAMAPK1 | |
| SCHEMBL30752040 | 0.81 | LMNA (0.41) | ALDH1A1MAPTLMNAPOLBMEN1 | |
| SCHEMBL6400980 | 0.79 | SIGMAR1 (0.58) | ALDH1A1MAPTMAPK1HPGDPOLB | |
| SCHEMBL4682177 | 0.79 | SIGMAR1 (0.49) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL19773941 | 0.79 | HPGD (0.42) | CYP1A2ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL4682176 | 0.79 | SIGMAR1 (0.49) | ALDH1A1MAPTPOLBMEN1KMT2A | |
| SCHEMBL6400976 | 0.79 | SIGMAR1 (0.58) | ALDH1A1MAPTMAPK1HPGDPOLB | |
| SCHEMBL17237942 | 0.78 | ALDH1A1 (0.41) | CYP1A2ALDH1A1KDM4EMAPTLMNA | |
| SCHEMBL17237947 | 0.78 | HPGD (0.41) | CYP1A2ALDH1A1KDM4EMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1232398-A | IL-8 receptor antagonists | SMITHKLINE BEECHAM CORP (US) | 1999-10-20 | — | — | CN | claimed |
| US-20050171195-A1 | P2X7 antagonists for treating neuropathic pain | ABBOTT LABORATORIES | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171195-A1 | P2X7 antagonists for treating neuropathic pain | P2RX3, P2RX7, P2RX1 | CYP1A2 2356/4885ALDH1A1 1730/4885KDM4E 3084/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.