Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 15/20 | 0.36 |
| ▸ | HPGD | P15428 | 6/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.33 |
| ▸ | CASP2 | P42575 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.32 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4892684 | 0.72 | ALDH1A1 (0.41) | ALDH1A1GAASMN1; SMN2HSD17B10LMNA | |
| SCHEMBL23861784 | 0.64 | HPGD (0.40) | KDM4EHPGDALDH1A1GAASMN1; SMN2 | |
| SCHEMBL16163017 | 0.62 | PDE7A (0.54) | KDM4EHPGDALDH1A1SMN1; SMN2HSD17B10 | |
| SCHEMBL11536434 | 0.61 | MAOA (0.47) | KDM4EHPGDALDH1A1SMN1; SMN2CASP3 | |
| SCHEMBL23861832 | 0.58 | KDM4E (0.38) | KDM4EHPGDALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL21383782 | 0.57 | CRBN (0.45) | KDM4EHPGDALDH1A1GAASMN1; SMN2 | |
| SCHEMBL29603792 | 0.57 | CRBN (0.45) | KDM4EHPGDALDH1A1GAASMN1; SMN2 | |
| SCHEMBL29604423 | 0.57 | MAOA (0.41) | KDM4EHPGDALDH1A1HSD17B10LMNA | |
| SCHEMBL1789178 | 0.57 | MAOA (0.41) | KDM4EHPGDALDH1A1HSD17B10LMNA | |
| SCHEMBL24447629 | 0.56 | BACE1 (0.67) | SMN1; SMN2LMNAOPRM1OPRK1OPRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050038036-A1 | Stabilization patient; antidepressant; psychological disorders; mood cycles | PFIZER INC | 2005-02-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050038036-A1 | Stabilization patient; antidepressant; psychological disorders; mood cycles | MC2R, NR3C1, CRH | KDM4E 2567/4885HPGD 1682/4885ALDH1A1 1321/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.