Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2003787 | 0.81 | CA1 (0.56) | ALDH1A1GAAPARP1NPC1RAB9A | |
| SCHEMBL8060232 | 0.80 | ALDH1A1 (0.58) | ALDH1A1KMT2APOLBRXRACYP1A1 | |
| SCHEMBL919577 | 0.78 | ALDH1A1 (0.55) | ALDH1A1KMT2APOLBCYP3A4SMN1; SMN2 | |
| SCHEMBL28393758 | 0.77 | ALDH1A1 (0.48) | ALDH1A1KMT2APOLBRXRACYP1A1 | |
| SCHEMBL2089244 | 0.76 | ALDH1A1 (0.52) | ALDH1A1KMT2APOLBRXRAGAA | |
| 1,3,5-Trimethoxybenzene SCHEMBL28834629 | 0.76 | ALDH1A1 (0.79) | ALDH1A1KMT2APOLBRXRACYP1A1 | |
| SCHEMBL19333548 | 0.76 | ELANE (0.47) | ALDH1A1KMT2APOLBRXRAGAA | |
| SCHEMBL9970808 | 0.74 | KMT2A (0.53) | ALDH1A1KMT2APOLBRXRAGAA | |
| SCHEMBL16960587 | 0.74 | KMT2A (0.44) | ALDH1A1KMT2ACYP3A4NPC1RAB9A | |
| SCHEMBL28103049 | 0.74 | ALDH1A1 (0.44) | ALDH1A1KMT2APOLBRXRAPARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050171195-A1 | P2X7 antagonists for treating neuropathic pain | ABBOTT LABORATORIES | 2005-08-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050171195-A1 | P2X7 antagonists for treating neuropathic pain | P2RX3, P2RX7, P2RX1 | ALDH1A1 1730/4885KMT2A 4090/4885POLB 4769/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.