Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | RXRA | P19793 | 1/20 | 0.45 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16675176 | 0.88 | CES2 (0.52) | ALDH1A1KMT2ASMN1; SMN2GAACYP3A4 | |
| SCHEMBL15416194 | 0.82 | CA1 (0.66) | ALDH1A1KMT2APOLBRXRASMN1; SMN2 | |
| SCHEMBL919577 | 0.82 | ALDH1A1 (0.55) | ALDH1A1KMT2APOLBSMN1; SMN2CYP3A4 | |
| SCHEMBL30463307 | 0.81 | CES2 (0.59) | KMT2APOLBMEN1KDM4E | |
| SCHEMBL8048513 | 0.81 | CES2 (0.59) | KMT2APOLBMEN1KDM4E | |
| SCHEMBL9237989 | 0.81 | KMT2A (0.42) | ALDH1A1KMT2APOLBSMN1; SMN2GAA | |
| SCHEMBL11985728 | 0.81 | ELANE (0.46) | ALDH1A1KMT2APOLBSMN1; SMN2GAA | |
| SCHEMBL6403298 | 0.80 | ALDH1A1 (0.52) | ALDH1A1KMT2APOLBRXRACYP1A1 | |
| SCHEMBL11009763 | 0.80 | ALOX5 (0.51) | ALDH1A1KMT2ASMN1; SMN2GAACYP3A4 | |
| SCHEMBL1398350 | 0.79 | CES2 (0.58) | ALDH1A1KMT2ASMN1; SMN2GAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9745254-B2 | Two-step and one-pot processes for preparation of aliphatic diisocyanates | GREAT EASTERN RESINS INDUSTRIAL CO., LTD. (TW) | 2017-08-29 | — | — | US | claimed |
| US-20170015621-A1 | TWO-STEP AND ONE-POT PROCESSES FOR PREPARATION OF ALIPHATIC DIISOCYANATES | GREAT EASTERN RESINS INDUSTRIAL CO., LTD. (TW) | 2017-01-19 | — | — | US | claimed |
| US-9012676-B2 | Processes for producing aryl carbamates, isocynates and polyureas using diaryl carbonate | GREAT EASTERN RESINS INDUSTRIAL CO., LTD. (CN) | 2015-04-21 | — | — | US | claimed |
| US-20130079542-A1 | PROCESSES FOR PRODUCING ARYL CARBAMATES, ISOCYNATES AND POLYUREAS USING DIARYL CARBONATE | NATIONAL CHUNG HSING UNIVERSITY (TW) | 2013-03-28 | — | — | US | claimed |
| CN-108250406-B | Soft segment-containing polyurethane, polyisocyanate, polyurethane prepolymer, polyurethane elastomer and preparation method thereof | 大东树脂化学股份有限公司 | 2021-06-15 | — | — | CN | disclosed |
| US-9012676-B2 | Processes for producing aryl carbamates, isocynates and polyureas using diaryl carbonate | GREAT EASTERN RESINS INDUSTRIAL CO., LTD. (CN) | 2015-04-21 | — | — | US | disclosed |
| US-20130079542-A1 | PROCESSES FOR PRODUCING ARYL CARBAMATES, ISOCYNATES AND POLYUREAS USING DIARYL CARBONATE | NATIONAL CHUNG HSING UNIVERSITY (TW) | 2013-03-28 | — | — | US | disclosed |
| US-6143917-A | FROM A DIARYL CARBONATE AND AN AMINE COMPOUND HAVING AT LEAST ONE HYDROGEN ATOM LOCATED AT AN N-POSITION UNDER MODERATE CONDITIONS AT A HIGH REACTION RATE WITH A HIGH SELECTIVITY AND WITH A HIGH YIELD | UBE INDUSTRIES, LTD. (JP) | 2000-11-07 | — | — | US | disclosed |
| EP-0902014-A1 | PROCESS FOR PRODUCING ARYL CARBAMATES | UBE INDUSTRIES LIMITED (JP) | 1999-03-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130079542-A1 | PROCESSES FOR PRODUCING ARYL CARBAMATES, ISOCYNATES AND POLYUREAS USING DIARYL CARBONATE | UROD, DDC, TST | ALDH1A1 4595/4885KMT2A 1168/4885POLB 387/4885 |
| US-20170015621-A1 | TWO-STEP AND ONE-POT PROCESSES FOR PREPARATION OF ALIPHATIC DIISOCYANATES | PARG, CDIPT, CDS2 | ALDH1A1 2280/4885KMT2A 657/4885POLB 900/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.