Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL11654034 | 0.89 | — | — | |
| Potassium Ion SCHEMBL11659725 | 0.89 | — | — | |
| Potassium Ion SCHEMBL11654447 | 0.89 | — | — | |
| Potassium Ion SCHEMBL11656809 | 0.89 | — | — | |
| Potassium Ion SCHEMBL11651998 | 0.89 | — | — | |
| Potassium Ion SCHEMBL11877330 | 0.89 | — | — | |
| Methylamine SCHEMBL11876958 | 0.82 | — | — | |
| SCHEMBL11655088 | 0.75 | — | — | |
| SCHEMBL2163370 | 0.75 | — | — | |
| Lithium Ion SCHEMBL555214 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6313292-B1 | REACTION FROM 5-AMINO-2-FLUOROPYRIDINE; AMINATION, CYCLIZATION, CHLORINATION, SALT FORMATION, DECHLORINATION, DEBLOCKING | WARNER-LAMBERT COMPANY | 2001-11-06 | — | — | US | claimed |
| WO-1997026259-A1 | IMPROVED PROCESS FOR PREPARING 4,6-DISUBSTITUTED PYRIDO[3,4-d]PYRIMIDINES | WARNER-LAMBERT COMPANY (US) | 1997-07-24 | — | — | WO | claimed |
| US-4051185-A | PROCESS FOR THE RECLAMATION OF ALKALI METAL ALKYLAMIDES | ATOMIC ENERGY OF CANADA LTD. (CA) | 1977-09-27 | — | — | US | claimed |
| US-4007257-A | Alkali metal hydride formation | ATOMIC ENERGY OF CANADA LIMITED (CA) | 1977-02-08 | — | — | US | claimed |
| US-9073817-B2 | Efficient process to induce enantioselectivity in procarbonyl compounds | LAURUS LABS PRIVATE LIMITED (IN) | 2015-07-07 | — | — | US | disclosed |
| EP-2462935-B1 | Process for the preparation of tenofovir | LAURUS LABS PRIVATE LTD (IN) | 2015-01-21 | — | — | EP | disclosed |
| US-8791259-B2 | Process for the preparation of Tenofovir | LAURUS LABS PRIVATE LIMITED (IN) | 2014-07-29 | — | — | US | disclosed |
| US-20130165413-A1 | PROCESS FOR THE PREPARATION OF TENOFOVIR | APTUIT LAURUS PRIVATE LIMITED (IN) | 2013-06-27 | — | — | US | disclosed |
| US-20120264933-A1 | EFFICIENT PROCESS TO INDUCE ENANTIOSELECTIVITY IN PROCARBONYL COMPOUNDS | LAURUS LABS PRIVATE LIMITED (IN) | 2012-10-18 | — | — | US | disclosed |
| WO-2012081032-A1 | PROCESS FOR THE PREPARATION OF TENOFOVIR | APTUIT LAURUS PRIVATE LIMITED (IN) | 2012-06-21 | — | — | WO | disclosed |
| EP-2462935-A1 | Process for the preparation of tenofovir | Laurus Labs Private Limited (IN) | 2012-06-13 | — | — | EP | disclosed |
| US-20050014840-A1 | Thiol sulfonamide metalloprotease inhibitors | PHARMACIA CORPORATION | 2005-01-20 | — | — | US | disclosed |
| US-4107207-A | HYDROGEN-DEUTERIUM, DEUTERIUM ENRICHMENT | ATOMIC ENERGY OF CANADA LIMITED (CA) | 1978-08-15 | — | — | US | disclosed |
| US-4051185-A | PROCESS FOR THE RECLAMATION OF ALKALI METAL ALKYLAMIDES | ATOMIC ENERGY OF CANADA LTD. (CA) | 1977-09-27 | — | — | US | disclosed |
| US-4051185-A | PROCESS FOR THE RECLAMATION OF ALKALI METAL ALKYLAMIDES | ATOMIC ENERGY OF CANADA LTD. (CA) | 1977-09-27 | — | — | US | disclosed |
| US-4007257-A | Alkali metal hydride formation | ATOMIC ENERGY OF CANADA LIMITED (CA) | 1977-02-08 | — | — | US | disclosed |
| US-3995017-A | METHYLAMIDES OF ALKALI METALS IN METHYLAMINE | ATOMIC ENERGY OF CANADA LIMITED (CA) | 1976-11-30 | — | — | US | disclosed |
| US-3983243-A | INSECTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1976-09-28 | — | — | US | disclosed |
| US-3962428-A | JUVENILE HORMONE | HOFFMANN-LA ROCHE INC. (US) | 1976-06-08 | — | — | US | disclosed |
| US-3961051-A | INSECTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1976-06-01 | — | — | US | disclosed |